| abstract |
A compound represented by the formula (I) or a pharmaceutically acceptable salt thereof: (I) wherein R represents a branched alkyl group having 3 to 9 carbon atoms or the like; R represents a 6-membered heteroaryl group having 1 or 2 nitrogen atoms or the like; R represents a hydrogen atom, an alkanoylamino group or the like; R represents a hydrogen atom, a lower alkyl group or the like; X represents an oxygen or sulfur atom; X represents an oxygen atom or a single bond; and m is an integer of 0 to 4. This compound has a metabotropic glutamate receptor 1 inhibitory effect, and therefore is useful for the treatment of a brain disorder such as convulsion, acute pain, inflammatory pain, chronic pain, cerebral infraction or transient cerebral ischemic attack, a mental dysfunction such as schizophrenia, and a disease such as anxiety and drug addiction. |