Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39c68430bcb778feae2ad4e9640ad0ca |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3233 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3145 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65613 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65583 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
filingDate |
2005-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2011-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5073ee35383c85dcba1381809ee2b7e9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a15a6939db2e3304dc3e68eba1c921fe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb0c321b9ed756adc08a8a34a19cacc7 |
publicationDate |
2011-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
AU-2005327188-C9 |
titleOfInvention |
Antisense antibacterial method and compound |
abstract |
A method and antisense compound for inhibiting the growth of pathogenic bacterial cells are disclosed. The compound contains no more than 12 nucleotide bases and has a targeting nucleic acid sequence of no fewer than 10 bases in length that is complementary to a target sequence containing or within 10 bases, in a downstream direction, of the translational start codon of a bacterial mRNA that encodes a bacterial protein essential for bacterial replication. The compound binds to a target mRNA with a T of between 50 °C to 60 °C. The relatively short antisense compound are substantially more active than conventional antisense compounds having a targeting base sequence of 15 or more bases. |
priorityDate |
2004-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |