http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2005254736-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f1fbb22d7954557801160a9fd579bae9 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-8121 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-81 |
| filingDate | 2005-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9bc3500948e09ff725dac4dd5eeb42da http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b326f227e93fd3a2e35fa54f5920397 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d4ecd37540eb89a37a46b0eb0f0fcb1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62b8cd9e2e61f58dcfc1604da5aa94a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9943242ec7ae9859a666b29090885a6c |
| publicationDate | 2011-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AU-2005254736-B2 |
| titleOfInvention | Oligomeric peptides and their use for the treatment of HIV infections |
| abstract | The invention relates to oligomeric peptides with biological activity against HIV infection having the amino acid sequence (Z-LEX X-X-P-X5-X-X-X- X-X-K-X-X-X-X-X-Z), wherein n indicates the number of monomeric peptide chains, whereby n is 2, 3 or 4; X is a lysine, alanine, or aspartic acid; X is a cysteine, methionine or isoleucine; X is a serine, cysteine, lysine or glycine; X is an isoleucine, alanine, phenylalanine or cysteine; X5 is a proline, D-proline or a substituted L-or D-proline; X is a cysteine or glutamic acid; X is an amino acid with a hydrophobic or an aromatic side chain or cysteine; X is an amino acid with a hydrophobic or an aromatic side chain or cysteine; X is an amino acid with an aromatic side chain; X is a glycine, alanine or asparagine; X is a proline, aspartic acid, octahydroindolyl-2-carboxylic acid or D1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; Xis a phenylalanine, alanine, glycine, glutamic acid or D-1,2,3,4tetrahydroisoquinoline-3-carboxylic acid; Xis an amino acid with a hydrophobic or an aromatic side chain; Xis an amino acid with a hydrophobic or an aromatic side chain; X is a phenylalanine or deletion; Z is NH or a sequence of 1 to 10 amino acid residues; Z is COOH or a sequence of 1 to 10 amino acid residues; and oligomeric peptides which are fragments thereof and/or derivatives, especially amidated, alkylated, acylated, sulfated, pegylated, phosphorylated and/or glycosylated derivatives, and mutants thereof; and with the proviso that (a) if Xis alanine, glycine, glutamic acid, or D-1,2,3,4tetrahydroisoquinoline-3-carboxylic acid than X, X and Xare phenylalanine, valine and phenylalanine respectively; and/or (b) if Xis phenylalanine, than X, X and Xare valine, phenylalanine and a deletion, respectively; and (c) there are at maximum three cysteine residues in a peptide; and (d) the oligomeric peptide has not the sequence (LEAIPCSIPPEFLFGKPFVF) (VIR-576); and (e) the monomeric peptide chains are not linked by peptide bonds between the N- terminus of one peptide chain to the C-terminus of another peptide chain. |
| priorityDate | 2004-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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