http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2005246415-B8

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filingDate 2005-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2011-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_817122575e5f51ca4503762c6c22437b
publicationDate 2011-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber AU-2005246415-B8
titleOfInvention Optical sensor with layered plasmon structure for enhanced detection of chemical groups by SERS
abstract An optical sensor and method are disclosed for use with a visible-light laser excitation beam (60) and a Raman spectroscopy detector, for detecting the presence chemical groups in an analyte (80) applied to the sensor. The sensor includes a substrate (10), a plasmon resonance mirror (20) formed on a sensor surface of the substrate (10), a plasmon resonance particle layer (40) disposed over the mirror (20), and an optically transparent dielectric layer (30) about 2-40 nm thick separating the mirror (20) and particle layer (40). The particle layer (40) has a periodic array of plasmon resonance particles with (i) a coating to binding analyte molecules (80), (ii) substantially uniform particle sizes and shapes in a range between 50-200 nm (ii) a particle-to-particle spacing less than the wavelength of the laser excitation beam. The device is capable of detecting single analyte molecules (80) with an amplification factor of up to 10­ 10.
priorityDate 2004-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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