| abstract |
The invention provides a powdered formulation which is a freeze-dried mixture of a sensitive active material and an excipient containing: 0.1 - 50 % by wt of the sensitive active material, 50 - 99.99 % by wt of the excipient, wherein at least 0.1 % by wt of the mixture is an amorphous state; the formulation has a substantially reduced hygroscopicity. |