http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AT-500321-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_db7d4e0431c54e1e1ec328b91f7239f6 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate | 2003-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1922b9ee29da4945cdfe691f0d8a8924 |
| publicationDate | 2005-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AT-500321-A1 |
| titleOfInvention | METHOD FOR DIAGNOSIS OF THE DOWN SYNDROME |
| abstract | A method for diagnosis of Down syndrome (DS), comprsing detecting the levels of phosphoinisitolglycan peptide (PIG-P; DSCR5); DCSR6 and potassium inwardly rectifying channel protein KIR3.2 (GIRK2) (DSCRP = Down syndrome critical region protein), is new. Method for diagnosis of Down syndrome (DS) comprises: (a) providing a sample of amniotic fluid, blood or serum from a pregnant woman or a brain tissue sample; (b) determining the amount (x) of at least one of the proteins phosphoinisitolglycan peptide (PIG-P; DSCR5); DCSR6 and potassium inwardly rectifying channel protein KIR3.2 (GIRK2) (DSCRP = Down syndrome critical region protein); (c) comparing x with the standard amount (y) for the proteins in a corresponding non-DS sample; and (d) diagnosing DS if x is lower than y for GIRK2 or x is higher than y for the other two proteins. An independent claim is included for a kit for determining the amount of at least two of the specified proteins comprising a sample container; agents (especially antibodies) for detecting the proteins and agents for quantifying the amount of detected proteins. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113063952-A |
| priorityDate | 2003-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.