http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AT-4589-U2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac2c17e532220d91aca9a28ef60f178b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D21C5-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D21C5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06 |
| filingDate | 2000-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2001-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AT-4589-U2 |
| titleOfInvention | OXYCODON COMPOSITION WITH CONTROLLED RELEASE |
| abstract | A method of significantly reducing the range of daily dose dosages needed to control pain in approximately 80% of patients is disclosed, comprising an oral, solid, controlled release dosage formulation comprising from about 10 to about 40 mg of oxycodone or a salt thereof is administered to a patient. The formulation ensures an average maximum plasma concentration of oxycodone of about 6 to about 60 ng / ml from about 2 to about 4.5 hours after administration, and from about 10 to about 14 hours after repeated "q12h" ( ie every 12 hours) administration a mean minimum plasma concentration of about 3 to about 30 ng / ml under steady-state conditions. Another embodiment relates to a method for significantly reducing the range of daily doses required to control pain in essentially all patients. Figure 5 is a graph showing the mean oxycodone plasma concentration of a 10 mg controlled release oxycodone formulation and a study reference standard made in accordance with the present invention. |
| priorityDate | 1991-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.