http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AT-404725-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e94091a4fc81b8d0237117707cc7ee |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-06 |
| filingDate | 1997-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1999-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1999-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AT-404725-B |
| titleOfInvention | METHOD FOR PRODUCING ANTI-HYPERCHOLESTERINEMICALLY ACTIVE TETRAZOLE COMPOUNDS |
| abstract | Process for the preparation of compounds which have antihypercholesterolaemic activity and the formula XIII <IMAGE> essentially in the trans-(4R,6S) form, where R1 and R2 are each, independently of one another, hydrogen, halogen, C1-4-alkyl, C1-4-alkoxy or trifluoromethyl and R2, R3, R5 and R6 are each, independently of one another, hydrogen, halogen, C1-4-alkyl or C1-4-alkoxy, by reacting a compound of the general formula X <IMAGE> in which Z is <IMAGE>, in which R13 is C1-4-alkyl, R14 is phenyl which is optionally substituted by one or two C1-4-alkyl or chloro substituents, and X is bromine, chlorine or iodine, with a compound of the formula <IMAGE> essentially in the cis-(4R,6S) form, in which R9 and R10 are each C1-4-alkyl or R9 and R10 represent together with the carbon atom to which they are bonded cyclopentyl, cyclohexyl or cycloheptyl and R12 is hydrogen, C1-4-alkyl or a metal cation, elimination of the protective group and cyclization to form the compound of the formula XIII. |
| priorityDate | 1988-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 128.