| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bba842fc4d37dfcaced1b55bc0c91c7c |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-415
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4164
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-341
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-381
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-404
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-437 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-405
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-04 |
| filingDate |
1995-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1996-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
1996-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
AT-401872-B |
| titleOfInvention |
STABILIZED PHARMACEUTICAL AGENT, CONTAINING FLUVASTATIN SODIUM AS AN ACTIVE SUBSTANCE |
| abstract |
The compsn. (I) comprises HMG-CoA cpd. of formula R-X-CH(OH)-CH2-CH(OH)-CH2-COOM (II) and an alkaline medium (III) imparting pH of at least 8 to an aq. soln. or dispersion. R = organic radical; X = -CH=CH-; and M = physiologically acceptable cation. (II) is pref. associated with carbonate(s) e.g. a mixt. of (i) water soluble and (ii) water insol. or sparingly soluble carbonates in a ratio of (i) to (ii) of 1.4-2:1. (II) is pref. fluvastatin sodium and (i) is pref. caclium carbonate and (ii) is pref. Na (bi)carbonate. (I) pref. comprises 0.5-60 wt.% (II), 0.5-40 wt.% Ca carbonate, 0.5-20 wt.,% Na bicarbonate and 10-65 wt.% microcystalline cellulose. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SG-160185-A1 |
| priorityDate |
1991-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |