http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AT-401521-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_27a71ddaaa2f5a8c228fc6cb3f3b3098 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J31-00 |
| filingDate | 1991-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1996-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1996-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AT-401521-B |
| titleOfInvention | METHOD FOR PRODUCING NEW ANDROSTANCARBOTHIOATS |
| abstract | The invention relates to the preparation of novel androstanecarbothioates I which have antiinflammatory activity and in which R1 is a fluoro-, chloro- or bromomethyl group or a 2-fluoroethyl group, R2 is a COR6 group in which R6 is a C1-3-alkyl group, or OR2 and R3 together represent a 16α, 17α- isopropylidenedioxy group, also R3 is a hydrogen atom, a methyl group or a methylene group, R4 is a hydrogen, chlorine or fluorine atom, R5 is a hydrogen or fluorine atom, and the symbol <IMAGE> means a single or double bond, wherein (a) a compound I with protected 11β-hydroxyl group is freed of the protective group, (b) a compound I with a substituent-free 9,11 double bond in position 11 is reacted with a reagent introducing a 9α-halo, 11β-hydroxy grouping, or (c) a compound I in which <IMAGE> is a double bond is partly reduced to a compound I in which <IMAGE> is a single bond. <IMAGE> |
| priorityDate | 1980-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 77.