http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AT-401061-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da2a3c0735501546378b72cb4df0ee2c |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-26 |
| filingDate | 1995-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1996-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1996-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AT-401061-B |
| titleOfInvention | USE OF A HUMAN MONOCYTE-LIKE CELL LINE FOR IDENTIFICATION AND DETERMINATION OF SUBSTANCES FOR INHIBITING THE HUMAN ENZYME CYCLOOXYGENASE-2 |
| abstract | Method for the identification and quantitative determination of substances which inhibit the human enzyme cyclooxygenase-2, characterized in that a) cells of a non-genetically manipulated clone of the human cell line Mono Mac 6 are stimulated with suitable growth and/or differentiation factors, the cells stimulated in this way are incubated together with potential inhibitors of cyclooxygenase-2 and after addition of arachidonic acid the concentration or amount of the products of cyclooxygenase metabolism in the culture supernatant of these cells is measured using a suitable detection method, or b) cells of a non-genetically manipulated clone of the human cell line Mono Mac 6 are incubated with potential inhibitors of cyclooxygenase-2, these cells are then stimulated with suitable growth and/or differentiation factors, and after addition of arachidonic acid the concentration or amount of the products of cyclooxygenase metabolism in the culture supernatant of these cells is measured using a suitable detection method. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AT-402936-B |
| priorityDate | 1995-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.