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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_269bec07ec746f841d7f0b52c55e93da
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_48d62bd1936e6da8be0ba8bbdaa3f5cd
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H3-06
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H3-06
filingDate 1992-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1993-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1993-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber AT-396474-B
titleOfInvention NEW D-GLUCOSAMINE DERIVATIVES
abstract D-glucosamine derivs. of formula (I) and (II) are new where R is alkenyl, aminoalkyl and R1 is H and acyl D-glucosamine derivs. of formula (III) are also new. Where Ra is H, alkyl, alkenyl, aminoalkyl and R1 is H or acyl. Prodn. of (I) and (II) comprises reacting D-glucosamine derivs. of formula (IV) with L-fucose derivs. of formula (V). In (IV) Rb is alkyl, alkenyl, aryl, R1 is acyl R2 and R3 are bifunctional, alkyl silyl, alkylidene, arylidene, protective gp. and R4 is H or, independently of R3 and R4 a bifunctional protective gp. as above. The reaction is carried out in an inert solvent e.g. ether or (N,N-dimethylformamide using heavy metal salts e.g. silver or mercury salts or thiophillic reagents as catalysts. In (V), Rc is halogen, thioalkyl, trichloracetimidate, R2 is arylmethyl R3 and R4 are alkyl, aryl, acyl, alkylider or arylidene. The prod. is chromatographically purified and the protective gps. removed.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004031244-A1
priorityDate 1992-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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