| abstract |
A 1,3,5-trithiane derivative (formula I) in which R<1> is hydrogen, R<2> is hydrogen, hydroxyl or imidazolyl, or R<2> and R<1> together form a double bond, R<3> is hydrogen; unsubstituted or substituted phenyl; a heteroaromatic group, a polycyclic fused ring, substituted C1-C5 alkyl or halostyryl, or R<3> together with R<2> forms C1-C9 alkylidene, R<4> is hydrogen, optionally substituted C1-C8 alkyl, C15-C20 alkylene, unsubstituted or substituted phenyl, or R<3> and R<4> together are a fluoren-9-ylidene group, l, m and n are zero, 1 or 2, and R<4> is not a phenyl group when R<3> is a phenyl group, and pharmaceutical preparations containing the compounds of the formula I, and preparation process. <IMAGE> |