| abstract |
Claim 1: A vaccine composition comprising an injectable oil-in-water (Ab/Ag) emulsion, characterized in that it comprises: (i) an aqueous solution comprising at least one immunogen; (ii) an aqueous solution comprising a hydrophilic ionic surfactant; (iii) an optional aqueous solution comprising aluminum hydroxide; (iv) a mineral oil; (v) a lipophilic nonionic surfactant; (vi) a hydrophilic nonionic surfactant having a high hydrophilic-lipophilic balance (HLB) value of between 13 and 40; and (vii) a hydrophilic nonionic surfactant having a low hydrophilic-lipophilic balance (HLB) value of between 9 and 13. |