Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a73cee5001ad08339ae751c10d9abf71 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 |
filingDate |
2020-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22b9e60f5d2fdadf7b5b76909f72ecb0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5aa9adb79b91cc60a0082ed1f17b426 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b132d36eb2519e6fc743d9f1059fbae |
publicationDate |
2022-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
AR-120109-A1 |
titleOfInvention |
PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS AS IMMUNOMODULATORS |
abstract |
The present description relates to compounds of formula (1) that modulate PD-1/PD-L1 protein/protein interaction, compositions and methods for treating various diseases, including infectious diseases and cancer. Claim 1: A compound of formula (1) or a pharmaceutically acceptable salt thereof, characterized in that: R¹ is CH₃ or Cl; R² is a compound of the group of formulas (2); R³ is H or CH₃; R⁴ is H or CH₃; and R⁵ is H or CH₃. |
priorityDate |
2019-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |