http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-119913-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8bb2c65fed767c6cdb08ca3b49dbb9f0 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D407-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 |
| filingDate | 2020-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_457b7178efb5bb74cbdaa64d2772015c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d27794678ecff2bb2b743ccc9db723a |
| publicationDate | 2022-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-119913-A1 |
| titleOfInvention | RIP1 INHIBITOR COMPOUNDS AND METHODS FOR MANUFACTURING AND USING THE SAME |
| abstract | Kinase inhibitory compounds, such as receptor-interacting protein-1 (RIP1) kinase inhibitory compounds as well as pharmaceutical compositions and combinations comprising such inhibitory compounds are disclosed herein. The disclosed compounds, pharmaceutical compositions, and/or combinations can be used to treat or prevent a kinase-associated disease or condition, particularly a RIP1-associated disease or condition. Claim 1: A compound, having a formula (1) or a pharmaceutically acceptable salt thereof, wherein: ring B is 5-membered or 6-membered heteroaryl wherein heteroaryl has (a) one, two or three atoms of nitrogen in the ring and the rest of the atoms in the ring are carbon; or (b) one or two nitrogen atoms and one oxygen atom with the proviso that R¹ is heterocyclyl, -C& |
| priorityDate | 2019-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.