http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-119466-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b214db43fd81f8f1a46db2fecbded40b |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-04 |
| filingDate | 2020-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ce453e9efe11880318b16bd2f3fa3f6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d0771a3ac152d79e19839b2a6da368c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b4c1674dbb04fa36da7a8c779d9196d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b44c6cb9613c364a4bc28fdfedaef3c |
| publicationDate | 2021-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-119466-A1 |
| titleOfInvention | DERIVATIVES OF PICOLINAMIDE AND 2-THIOXO-4H-PYRIDO[2,3-e][1,3]OXAZIN-4-ONE AND THEIR USE AS FUNGICIDES |
| abstract | Picolinamide and pyrido[2,3-e][1,3]oxazine derivatives having fungicidal activity, fungicidal compositions comprising them and their use in the control of fungal plant diseases. Claim 1: A compound of formula (1), or an agronomically acceptable salt or N-oxide thereof, Y¹ is independently selected from O or S; each R¹, R⁵ᵃ and R¹⁵ are independently selected at each occurrence from C₁₋₆ alkyl, C₁₋₆ haloalkyl, C₃₋₆ cycloalkyl, halogen, nitro, OR¹¹, SR¹², OS(O)₂R¹², S(O)₂R¹², C (O)OR¹², C(O)NR¹²R¹², C(O)R¹², S(O)₂NR¹²R¹², S(O)(NR¹²)R¹², S(O)R¹², cyano, C₂₋₆ alkenyl, C₂₋₆ alkynyl, and NR¹²R¹³; each R² and R³ are independently selected from H, C₁₋₄ alkyl, C₃₋₆ cycloalkyl, C(O)R¹⁴, C(O)OR¹⁴, CH₂OC(O)R¹⁴, and CH₂OC(O)OR¹⁴; R⁴ is independently selected at each occurrence from: H, C₃₋₆ cycloalkyl, C₁₋₆ alkyl, and benzyl; or R³ and R⁴ together form a group independently selected from C₁₋₂ alkylene, -C(O)- and -C(S)-; R⁵ is a 10-membered heteroaryl group selected from quinoline, isoquinoline, and quinazoline; where R⁵ is substituted with 1 to 5 R⁵ᵃ groups and/or a single Z¹-Z²-R⁶ group; Z¹ is independently absent or is CR⁸R⁹; Z² is independently absent or selected from C(O)O, OC(O), O, S, S(O), S(O)₂, C(O)NR⁷, NR⁷C(O), S(O )₂NR⁷, NR⁷S(O)₂, S(O)NR⁷, NR⁷S(O), CR⁸R⁹, C(O), C(S), C=NOR¹⁰, and NR⁷; R⁶ is independently selected at each occurrence from C₃₋₈ alkyl and C₀₋₃-R⁶ᵃ alkylene; where R⁶ᵃ is independently selected at each occurrence from phenyl, 5- or 6-membered heteroaryl, 5-, 6-, 7-, or 8-membered heterocycloalkyl, and C₅₋₈ cycloalkyl; said heterocycloalkyl or cycloalkyl group is monocyclic or bicyclic; said heteroaryl or phenyl group is optionally substituted with 1 to 5 R¹⁵ groups or said heterocycloalkyl or cycloalkyl group is optionally substituted with 1 to 4 R¹⁶ groups; R¹⁶ is independently selected at each occurrence from: =O, =S, C₁₋₆ alkyl, C₁₋₆ haloalkyl, C₃₋₆ cycloalkyl; halogen, nitro, OR¹¹, SR¹², OS(O)₂R¹², S(O)₂R¹², S(O)₂NR¹²R¹², S(O)(NR¹²)R¹², S(O)R¹², cyano, C₂₋₆ alkenyl, C₂ alkynyl ₋₆, and NR¹²R¹³; each R⁷ and R¹² are independently selected at each occurrence from: H, C₃₋₆ cycloalkyl, C₁₋₆ alkyl, and benzyl; or where two R¹² groups are attached to the same nitrogen atom, said R¹² groups, together with said nitrogen atom form a 4-, 5-, 6- or 7-membered heterocycloalkyl ring; R⁸ is independently selected at each occurrence from: H, C₃₋₆ cycloalkyl, C₁₋₆ alkyl, phenyl, and 5- or 6-membered heteroaryl; R⁹ is independently selected at each occurrence from: H, halo and OR¹⁰; or R⁸ and R⁹ together with the carbon atom to which they are attached may form a 3-, 4-, 5- or 6-membered C₃₋₆ cycloalkyl ring or heterocycloalkyl ring; each R¹⁰ is independently selected at each occurrence from: H, C₃₋₆ cycloalkyl, C₁₋₆ alkyl, and C₁₋₃-R¹⁰ᵃ alkylene; where R¹⁰ᵃ is independently selected at each occurrence from phenyl and 5- or 6-membered heteroaryl; R¹¹ is independently selected at each occurrence from: H, C₁₋₆ alkyl, C₃₋₆ cycloalkyl, C(O)-C₁₋₆ alkyl, and C₁₋₆ haloalkyl; R¹³ is independently selected at each occurrence from: H, C₁₋₆ alkyl, C(O)-C₁₋₆ alkyl, and S(O)₂-C₁₋₆ alkyl; or where an R¹² group and an R¹³ group are attached to the same nitrogen atom, said R¹² and R¹³ groups together with said nitrogen atom form a 4-, 5-, 6- or 7-membered heterocycloalkyl ring; R¹⁴ is independently selected at each occurrence: C₁₋₆ alkyl, phenyl, benzyl, and C₃₋₆ cycloalkyl; n is independently an integer selected from 0, 1 and 2; m is independently an integer selected from 0, 1, 2 and 3; p is independently an integer selected from 0, 1, 2, 3 and 4; q is independently an integer selected from 0 and 1; and where any alkyl, alkylene, alkenyl, cycloalkyl, heterocycloalkyl (including whether two R¹² groups or one R¹² group and one R¹³ group together with a nitrogen to which they are attached form a heterocycloalkyl ring), alkynyl, alkyl-C(O), alkyl -S(O)₂ and benzyl mentioned above is optionally substituted, if chemically possible, by 1 to 4 substituents each independently selected from the group consisting of: =O; =NRᵃ, =NORᵃ, C₁₋₄ alkyl, halo, nitro, cyano, C₁₋₄ haloalkyl, C₂₋₄ alkenyl, C₂₋₄ alkynyl, NRᵃRᵇ, S(O)₂Rᵃ, S(O)Rᵃ, S(O) (NRᵃ)Rᵃ, S(O)₂NRᵃRᵃ, CO₂Rᵃ, C(O)Rᵃ, CONRᵃRᵃ, ORᵃ and SRᵃ; where Rᵃ is independently selected from H and C₁₋₄ alkyl; and Rᵇ is independently selected from H, C₁₋₄ alkyl, C(O)-C₁₋₄ alkyl, and S(O)₂-C₁₋₄ alkyl. |
| priorityDate | 2019-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 38.