http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-118235-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_baee372c55802742f9582e25c15ff11a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-147 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-147 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-22 |
| filingDate | 2020-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ab545f94a8bb6f506cd7ecd3ee0db8c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad6c8922892a05da3a92fa4b96d32677 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c59aa81cc3deec46570036bc75529700 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1aacf44bdf7ff68a9716dde630283cbb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ebe13c9306584189810b329f4899a6b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3000d6d8b0dcf7714630a5d55bda45a6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5559847434048a77f451260c10203b1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29bae6ef1b5c4e47434fe4b27c8c64bc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dec69af2b71aed078991fc6f6fce67e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2016c3a2bf15db79e76c174429ba0b47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f220d8cc1935ac44e93596a734bbaa13 |
| publicationDate | 2021-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-118235-A1 |
| titleOfInvention | PENTACYCLIC HETEROCYCLES |
| abstract | Claim 1: Compound characterized in that it is selected from the group consisting of (3aS,14aR)-5-methyl-3,3a,5,6-tetrahydro-1H-benzofuro[3',2':4,5]pirimido[1, 2-a]cyclopenta[f][1,4]diazepin-4,13(2H,14aH)-dione: formula (1), (+)-7,7,12-trimethyl-1,2,3,6 ,7,10,11,12,13,15b-decahydropyrido[4'',3'':4',5']thieno[2',3':4,5]pyrimido[1,2-a]pyrrolo [2,1-c][1,4]diazepin-5,9-dione: formula (2), (3aS,14aR)-10-fluoro-5-methyl-3,3a,5,6-tetrahydro-1H -benzofuro[3',2':4,5]pyrimido[1,2-a]cyclopenta[f][1,4]diazepin-4,13(2H,14aH)-dione: formula (3), (3aS ,14aR)-5,8,10-trimethyl-3,3a,5,6-tetrahydro-1H-cyclopenta[f]pyrido[3'',2'':4',5']furo[3',2 ’:4,5]pyrimido[1,2-a][1,4]diazepin-4,13(2H,14aH)-dione: formula (4), (3aR,14aR)-10-fluoro-5-methyl -3,3a,5,6-tetrahydro-1H-benzofuro[3',2':4,5]pyrimido[1,2-a]cyclopenta[f][1,4]diazepin-4,13(2H, 14aH)-dione: formula (5), (3aR,14aR)-5-methyl-10-(trifluoromethyl)-3,3a,5,6-tetrahydro-1H-benzofuro[3',2':4,5] pyrimido[1,2-a]cyclopenta[f][1,4]diazepin-4,13(2H,14aH)-dione: formula ( 6), (3aS,14aR)-10-(2,2-difluoroethyl)-5-methyl-2,3,3a,5,6,9,10,11,12,14a-decahydro-1H-cyclopenta[f ]pyrido[4’’,3’’:4’,5’]thieno[2’,3’:4,5]pyrimido[1,2-a][1,4]diazepin-4,13-dione: formula (7), (3aS,14aR)-10-(2-methoxyethyl)-5-methyl-2,3,3a,5,6,9,10,11,12,14a-decahydro-1H-cyclopenta[f ]pyrido[4’’,3’’:4’,5’]thieno[2’,3’:4,5]pyrimido[1,2-a][1,4]diazepin-4,13-dione: formula (8), (3aS,14aR)-10-(difluoromethyl)-5-methyl-3,3a,5,6-tetrahydro-1H-benzofuro[3',2':4,5]pyrimido[1,2 -a]cyclopenta[f][1,4]diazepin-4,13(2H,14aH)-dione: formula (9), (2R,15bR)-2-fluoro-7,7,12-trimethyl-1, 2,3,6,7,10,11,12,13,15b-decahydro-5H,9H-pyrido[4'',3'':4',5']thieno[2',3':4, 5]pyrimido[1,2-a]pyrrolo[2,1-c][1,4]diazepin-5,9-dione: formula (10), (+)-(3a,14a-cis)-5, 10-dimethyl-1,3,3a,5,6,9,10,11,12,14a-decahydrofuro[3,4-f]pyrido[4'',3'':4',5']thieno[ 2',3':4,5]pyrimido[1,2-a][1,4]diazepin-4,13-dione: formula (11), (3aS,14aS)-5-methyl-10-(trifluoromethyl )-2,3,3a,5,6,14a-hexahydro-1H-benzofuro[3',2':4,5]pyrimido[1,2-a]cyclopenta[f][1,4]diaze pin-4,13-dione: formula (12), (-)-12-(2-methoxyethyl)-7,7-dimethyl-1,2,3,6,7,10,11,12,13,15b -decahydro-5H,9H-pyrido[4’’,3’’:4’,5’]thieno[2’,3’:4,5]pyrimido[1,2-a]pyrrolo[2,1-c ][1,4]diazepin-5,9-dione: formula (13), (3aR,14aR)-5,9-dimethyl-2,3,3a,5,6,8,9,10,11,14a -decahydro-1H-cyclopenta[f]pyrido[3'',4'':4',5']thieno[3',2':4,5]pyrimido[1,2-a][1,4] diazepin-4,13-dione: formula (14), (3aR,10R,14aR)-10-fluoro-2,5-dimethyl-2,3,3a,5,6,9,10,11,12,14a -decahydro-1H-benzo[4',5']thieno[2',3':4,5]pyrimido[1,2-a]pyrrolo[3,4-f][1,4]diazepin-4, 13-dione: formula (15), (3aS,14aS)-10-(2-methoxyethyl)-5-methyl-2,3,3a,5,6,9,10,11,12,14a-decahydro-1H -cyclopenta[f]pyrido[4'',3'':4',5']thieno[2',3':4,5]pyrimido[1,2-a][1,4]diazepin-4, 13-dione: formula (16), and (-)-(3a,14a-trans)-2-(2-fluoroethyl)-5-methyl-2,3,3a,5,6,14a-hexahydro-1H- benzofuro[3',2':4,5]pyrimido[1,2-a]pyrrolo[3,4-f][1,4]diazepin-4,13-dione: formula (17), or a salt pharmaceutically acceptable of it. |
| priorityDate | 2019-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 36.