http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-109976-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dab7fd26f3cb605aab550ed208a2fe8c |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00 |
| filingDate | 2017-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9248daad06afb26d32b46bbc337bb4a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1aac8053822d4ada2e40813b8ab5ab80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_728f9bda31ca24c69257c087e79d77ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75c0fcfc4ebbe8611b4be27d11337eac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1bd4425cb73c45128c58042bbb83c24e |
| publicationDate | 2019-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-109976-A1 |
| titleOfInvention | OXIESTEROLS AND METHODS FOR USE |
| abstract | The compounds herein are contemplated as useful for the prevention and treatment of NMDA-mediated disorders. Claim 1: A compound characterized in that it is of formula (1), or a pharmaceutically acceptable salt thereof, wherein: R¹ is alkyl; R² is hydrogen, alkyl, carbocyclyl, heterocyclyl, aryl, or heteroaryl and R³ is alkyl, carbocyclyl, heterocyclyl, aryl, or heteroaryl, or R² and R³, together with the carbon atom to which they are attached form a ring of between 3 and 8 members; each of R⁴ and R⁵ is independently hydrogen, halo, or -ORC, where RC is hydrogen or C₁₋₆ alkyl, or R⁴ R⁵, together with the carbon atom to which they are attached form an oxo group; R⁶ is absent or is hydrogen; and ⁻ ⁻ ⁻ ⁻ ⁻ represents a single or double bond, where when one of the ⁻ ⁻ ⁻ ⁻ ⁻ is a double bond, the other ⁻ ⁻ ⁻ ⁻ ⁻ is a single bond; when both of the ⁻ ⁻ ⁻ ⁻ ⁻ are simple bonds, then R⁶ is hydrogen; and when one of the ⁻ ⁻ ⁻ ⁻ ⁻ is a double bond, R⁶ is absent. |
| priorityDate | 2016-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.