http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-109975-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dab7fd26f3cb605aab550ed208a2fe8c |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-575 |
filingDate | 2017-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1aac8053822d4ada2e40813b8ab5ab80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1bd4425cb73c45128c58042bbb83c24e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9248daad06afb26d32b46bbc337bb4a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75c0fcfc4ebbe8611b4be27d11337eac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_728f9bda31ca24c69257c087e79d77ef |
publicationDate | 2019-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | AR-109975-A1 |
titleOfInvention | OXIESTEROLS AND ITS USE IN THE TREATMENT OR PREVENTION OF DISORDERS BY NMDA |
abstract | These compounds are contemplated as useful for the prevention and treatment of a variety of conditions, such as gastrointestinal disorders, autoimmune or inflammatory bowel diseases (IBD). Claim 1: A compound of formula (1), or a pharmaceutically acceptable salt thereof, wherein: each of R² and R³ is independently hydrogen, C₁₋₆ alkyl, carbocyclyl, or heterocyclyl, or R² and R³, together with the carbon atom to which they are attached form a ring of between 3 and 8 members; each of R⁴ and R⁵ is independently hydrogen, halo, or -ORC, where RC is hydrogen or alkyl (for example, C₁₋₆ alkyl), or R⁴ and R⁵, together with the carbon atom to which they are attached form a oxo group; R⁶ is absent or is hydrogen; and ⁻ ⁻ ⁻ ⁻ ⁻ represents a single or double bond, where when one of the ⁻ ⁻ ⁻ ⁻ ⁻ is a double bond, the other ⁻ ⁻ ⁻ ⁻ ⁻ is a single bond; when both of the ⁻ ⁻ ⁻ ⁻ ⁻ are simple bonds, then R⁶ is hydrogen; and when one of the ⁻ ⁻ ⁻ ⁻ ⁻ is a double bond, R⁶ is absent; with the proviso that compounds of formula (2) or (3) are excluded. |
priorityDate | 2016-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.