http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-109186-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7e6b011f44f29eda80156e4ab3438644 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61J3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4015 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 |
| filingDate | 2017-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5a92216dbe04ac776003ba89ee6f268 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f844edd7fcbbc9ff422d26f4e8498d21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba64251681ae1dca142d79a62fae93dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7a76fbf8ad5e79b6f484df06f87b22a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2fb172352a7553783cd0101e78a9808e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_336909a96bf624083bc108b48e56ba36 |
| publicationDate | 2018-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-109186-A1 |
| titleOfInvention | PROCEDURE FOR STABILIZATION OF GLICOPIRRONIUM BROMIDE PARTICLE SIZE |
| abstract | This provides a method for stabilizing the particle size of micronized glycopyrronium salt (such as glycopyrronium bromide) that provides a micronized product that has improved chemical and polymorphic stability even after prolonged storage. It also refers to compositions comprising said stabilized glycopyrronium salt (such as glycopyrronium bromide) and dry powder inhaler devices and capsules or blisters comprising the stabilized glycopyrronium salt (such as glycopyrronium bromide). The glycopyrronium salt (such as glycopyrronium bromide) or compositions herein can be used as a medicament, for example in the treatment of asthma, chronic obstructive pulmonary disease or cystic fibrosis or related diseases. Claim 1: Method for obtaining a stable glycopyrronium salt characterized in that it comprises the following steps: a) micronizing the glycopyrronium salt, optionally in the presence of one or more different active ingredients and / or excipients, to obtain a particle size distribution ( PSD) characterized in that a D₉₀ equal to or less than about 10 mm; b) curing the micronized glycopyrronium salt by keeping the product for at least 2 hours at a temperature between about 125 ° C and about 160 ° C. |
| priorityDate | 2016-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.