http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-108812-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bb75b0b19820e3833ebdcb31603b242b |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B61-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5383 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-04 |
| filingDate | 2017-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43e780c9f55c2f6fb0a7ae87cf990f8f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8808a38fa5225b438d23669b79dee498 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a3a007fc64796816b26ed75a8fc3de3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc917efc5d72478b731bf86923f761f8 |
| publicationDate | 2018-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-108812-A1 |
| titleOfInvention | PROCESS TO PREPARE A SUBSTITUTED AND CRYSTAL POLYCHYCLIC PIRIDONA DERIVATIVE |
| abstract | The present application provides a process for preparing a compound of formula (2), where R² is unsubstituted alkyl, characterized in that the reaction of a compound of formula (1), where R¹ is hydrogen or a protecting group other than alkyl does not substituted, with a compound of the formula: R²-OH, where R² is as defined above, in the presence of a sodium salt and/or a magnesium salt, and compounds. Claim 6: A process for preparing a compound of formula (4), wherein R³, R⁴, R⁵ and R⁶ are each independently hydrogen or halogen, with the proviso that one or two of R³, R⁴, R⁵ and R⁶ it is halogen; characterized in that the reaction of a compound of the formula (2'), with a compound of the formula (3), where R³, R⁴, R⁵ and R⁶ are as defined above. Claim 8: A process for preparing the compound of formula (5) or formula (6), characterized in that it comprises the process according to any of claims 1 to 7. Claim 9: A compound of formula (2') or a salt of this Claim 12: A compound of formula (4') or a salt thereof. Claim 15: A crystal of the compound of the formula (5), or a crystal of a pharmaceutically acceptable salt thereof. |
| priorityDate | 2016-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID458392451 |
Total number of triples: 22.