http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-108752-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_315ae544538aaeac6d1f4eed6754e4bb |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2602-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C235-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C213-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N37-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-25 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-60 |
| filingDate | 2017-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fca5c97dd4c46c0c2e8bab709aab98eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb95cde0b3b664cff338c7e27557479f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dd9a76f818894eae76f67f9d117adcb |
| publicationDate | 2018-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-108752-A1 |
| titleOfInvention | PROCESS TO CONVERT AN ENANTIOMER S IN ITS RACEMIC FORM |
| abstract | Process to convert the form of the unwanted S enantiomer into its useful racemic form with respect to a 4-aminoindane derivative. Claim 1: A process for the preparation of (R, S) -7-fluoro-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-amine having the formula (1), starting with (S) -7-Fluoro-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-amine having the formula (2), comprising the steps of: (a) acylating the (S ) -7-fluoro-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-amine and obtain an indanoamide derivative; (b) oxidizing said indanoamide derivative and obtaining a 3-hydroxyl indanoamide derivative; (c) dehydrate said 3-hydroxyl indanoamide derivative and obtain an indenoamide derivative; (d) deacylate said indenoamide derivative and obtain an indene amine derivative; and (e) hydrogenate said indene amine derivative and obtain the desired (R, S) -7-fluoro-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-amine. Claim 17: A compound of the formula (3) wherein R is selected from a C₁₋₆ alkyl group or a C₆₋₁₀ aryl group, these groups are optionally substituted with one or more C₁₋₆ alkyl groups and / or atoms of halogen Claim 21: A compound of the formula (4) wherein R is selected from a C₁₋₆ alkyl group or a C₆₋₁₀ aryl group, these groups are optionally substituted with one or more of C₁₋₆ alkyl groups and / or atoms Halogen |
| priorityDate | 2016-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.