http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-099241-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4b06c6a01554aac780c5441cb8253115 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F20-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-20 |
| filingDate | 2015-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f81921d69f6d13b4a4ece4dfa04fd389 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_284d5eb7d6edbd7ab2b143e4d27c7a39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_295ee5c2584c72ddc2f54f09560b310e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ceea2b0a8ec557956b41831ad54900d4 |
| publicationDate | 2016-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-099241-A1 |
| titleOfInvention | AFLATOXINE TEMPLATES, SYNTHESIS METHODS OF AN AFLATOXINE TEMPLATE COMPOSITE, MOLECULARLY PRINTED POLYMERIC INTERMEDIARY, METHOD OF PREPARATION OF A MOLECULARLY PRINTED POLYMER, MOLECULAR MULECOSETE SECRETARIAT MULECULAR SECTION |
| abstract | Claim 1: An aflatoxin template having a formula (1) characterized in that: R¹ is selected from H, C₁₋₆ alkyl, substituted C₁₋₆ alkyl and a halosubstituted C₁₋₆ alkyl; R² is selected from halo, C₁₋₆ alkyl, substituted C₁₋₆ alkyl, a halosubstituted C₁₋₆ alkyl, CH₂C (O) OR and CH (C (O) OR) ₂; wherein R is selected from H, C₁₋₆ alkyl and substituted C₁₋₆ alkyl; and R³ is selected from H, C₁₋₆ alkoxy and substituted C₁₋₆ alkyl. Claim 4: The aflatoxin template according to claim 1, characterized in that it is an isolated compound selected from the group consisting of the moieties of the group of formula (2) and combinations thereof. Claim 6: A synthesis method of an aflatoxin template, characterized by comprising: suspending a monoacid according to formula (3) in polyphosphoric acid and heating to at least 50 ° C; Cool the reaction mixture to less than 50 ° C and add an aqueous solution to obtain an aflatoxin template with the formula (4). Claim 15: A molecularly printed polymer comprising a crosslinked polymer made of a monomer, wherein the polymer has a plurality of cavities, characterized in that at least one of the cavities was prepared using the aflatoxin template having the formula (1) in where R¹ is selected from H, C₁₋₆ alkyl, substituted C₁₋₆ alkyl and a halosubstituted C₁₋₆ alkyl; R² is selected from halo, C₁₋₆ alkyl, substituted C₁₋₆ alkyl, a halosubstituted C₁₋₆ alkyl, CH₂C (O) OR and CH (C (O) OR) ₂; wherein R is selected from H, C₁₋₆ alkyl and substituted C₁₋₆ alkyl; and R³ is selected from H, C₁₋₆ alkoxy and substituted C₁₋₆ alkyl; or wherein R¹ together with R² form a C₄₋₇ cycloalkyl ring, a halo substituted C₄₋₇ cycloalkyl ring, an oxo substituted C₄₋₇ cycloalkyl ring, a C₄₋₇ cycloalkoxy ring, a C₄₋₇ substituted cycloalkyl ring hydroxy and a C₄₋₇ cycloalkyl ring substituted with carboxylic group; and R³ is selected from H, C₁₋₆ alkoxy and substituted C₁₋₆ alkyl. Claim 22: A method of preparing a molecularly printed polymer, characterized by comprising the steps of: providing an aflatoxin template having the formula (1) wherein R¹ is selected from H, C₁₋₆ alkyl, substituted C₁₋₆ alkyl and a halosubstituted C₁₋₆ alkyl; R² is selected from halo, C₁₋₆ alkyl, substituted C₁₋₆ alkyl, a halosubstituted C₁₋₆ alkyl, CH₂C (O) OR and CH (C (O) OR) ₂; wherein R is selected from H, C₁₋₆ alkyl and substituted C₁₋₆ alkyl; and R³ is selected from H, C₁₋₆ alkoxy and substituted C₁₋₆ alkyl; or wherein R¹ together with R² form a C₄₋₇ cycloalkyl ring, a halo substituted C₄₋₇ cycloalkyl ring, an oxo substituted C₄₋₇ cycloalkyl ring, a C₄₋₇ cycloalkoxy ring, a C₄₋₇ substituted cycloalkyl ring hydroxy and a C₄₋₇ cycloalkyl ring substituted with carboxylic group; and R³ is selected from H, C₁₋₆ alkoxy and substituted C₁₋₆ alkyl; combine the aflatoxin template with at least one monomer and one or more crosslinkers; polymerize the monomer and the one or more crosslinkers to form a molecularly printed polymeric intermediate; and removing the aflatoxin template from the molecularly printed polymeric intermediate to form a molecularly printed polymer. Claim 33: A method of sequestration of an aflatoxin, characterized by comprising: providing a molecularly printed polymer having a plurality of cavities, wherein at least one of the cavities is made using the aflatoxin template having the formula (1) in where R¹ is selected from H, C₁₋₆ alkyl, substituted C₁₋₆ alkyl and a halosubstituted C₁₋₆ alkyl; R² is selected from halo, C₁₋₆ alkyl, substituted C₁₋₆ alkyl, a halosubstituted C₁₋₆ alkyl, CH₂C (O) OR and CH (C (O) OR) ₂; wherein R is selected from H, C₁₋₆ alkyl and substituted C₁₋₆ alkyl; and R³ is selected from H, C₁₋₆ alkoxy and substituted C₁₋₆ alkyl; or wherein R¹ together with R² form a C₄₋₇ cycloalkyl ring, a halo substituted C₄₋₇ cycloalkyl ring, an oxo substituted C₄₋₇ cycloalkyl ring, a C₄₋₇ cycloalkoxy ring, a C₄₋₇ substituted cycloalkyl ring hydroxy and a C₄₋₇ cycloalkyl ring substituted with carboxylic group; and R³ is selected from H, C₁₋₆ alkoxy and substituted C₁₋₆ alkyl; providing a material, wherein the material optionally contains an aflatoxin; and contacting the molecularly printed polymer with the material. |
| priorityDate | 2015-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
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| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID457623688 |
Total number of triples: 16.