| abstract |
Claim 1: Compounds of formula (1) wherein X is N or CR³; Y is N or CR⁴; with the proviso that X and Y are not both N; A is a 9-membered bicyclic heteroaryl comprising two or three heteroatoms independently selected from N or O, wherein A may be optionally substituted with one, two or three R⁵; B is a saturated or partially unsaturated mono or bicyclic 4- or 9-membered heterocycloalkyl comprising one or two nitrogen atoms in the ring, the other atoms in the ring being carbon, in which B may be optionally substituted with one, two or three R⁶; R¹ is hydrogen, halo, C₁₋₇ alkyl, C₁₋₇ haloalkyl, C₁₋₇ alkoxy or C₁₋₇ haloalkoxy; R² is hydrogen, halo, C₁₋₇ alkyl, C₁₋₇ haloalkyl, C₁₋₇ alkoxy or C₁₋₇ haloalkoxy; R³ is hydrogen, halo, C₁₋₇ alkyl, C₁₋₇ haloalkyl, C₁₋₇ alkoxy or C₁₋₇ haloalkoxy; R⁴ is hydrogen, halo, C₁₋₇ alkyl, C₁₋₇ haloalkyl C₁₋₇ alkoxy or C₁₋₇ haloalkoxy; each R⁵ is independently selected from halo, cyano, C₁₋₇ alkyl, C₁₋₇ haloalkyl or C₃₋₇ cycloalkyl; each R⁶ is independently selected from C₁₋₇ alkyl or two R⁶ together form a C₂₋₇ alkylene; and pharmaceutically acceptable salts thereof. |