| abstract |
Compounds that exhibit acetyl-CoA carboxylase modulating activity and that are useful, for example, in methods for the control of fungal pathogens in plants. Claim 1: A method for controlling fungal pathogens, characterized in that the method comprises administering to a plant, a seed or the soil a composition comprising an effective amount of a compound of formula (1) or a salt thereof, wherein R¹ is selects from the group consisting of OH and N (R⁷R⁸), where R⁷ and R⁸ are independently selected from the group consisting of hydrogen, OH, and CH₃; R² is selected from the group consisting of alkyl, cycloalkyl, heterocycloalkyl, aryl, and heteroaryl, each of which may be optionally substituted with one or more substituents selected from the group consisting of halogen, CH₃, OCH₃, CF₃, OCF₃ , and CN; R³ is selected from the group consisting of hydrogen, CN, ethynyl, CH₂N (R⁹R¹⁰), and C (O) N (R⁹R¹⁰), where R⁹ and R¹⁰ are independently selected from each other from the group consisting of hydrogen and alkyl ; R⁴ is selected from the group consisting of haloalkyl, aryl, arylalkyl, heteroaryl, and heteroarylalkyl, each of which may be optionally substituted independently with one or more substituents selected from the group consisting of halogen, alkyl, alkoxy, haloalkyl, haloalkoxy, alkenyl, hydroxyalkyl, hydroxyl, N (R⁹R¹⁰), NR¹¹C (O) R¹², and O (CO) R¹³, where R⁹ and R¹⁰ are independently selected from the group consisting of hydrogen and alkyl, R¹¹ is selected Among the group consisting of hydrogen and alkyl, R¹² is alkyl, and R¹³ is alkyl; R⁵ is selected from the group consisting of hydrogen and alkyl; or R⁴ and R⁵ together form a fused cycloalkyl or heterocycloalkyl ring having between 5 and 6 ring atoms selected from the group consisting of carbon, nitrogen, and oxygen; R⁶ is selected from the group consisting of alkyl, haloalkyl, aryl, arylalkyl, heteroaryl, and heteroarylalkyl, each of which may be optionally independently substituted with one or more substituents selected from the group consisting of halogen, alkyl, alkoxy, haloalkyl, and haloalkoxy; or R⁵ and R⁶ together form a fused cycloalkyl or heterocycloalkyl ring having between 5 and 6 ring atoms selected from the group consisting of carbon, nitrogen, and oxygen; and E is selected from the group consisting of S, O, N (H), N (CH₃), and CH₂. |