http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-094773-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_872dd7cd609eb2a937dcfd303d521798 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D267-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D281-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-554 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 |
| filingDate | 2014-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3cadbd42793cae1e0492ddc0a9e8f8b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9397ab68eb7cfd2ccf688c4294e5c8d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb575c73391b984f3ddc69693c1a86ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ffe54efeaf2c00fdf2db7a282a49ad1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6736e4091f668078bc789104bab920c1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f5d4c888bb23206d8c752d13d6b8dec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82388397a3303c607420a009aebab9c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad25c23dd6afa10bfe118f007a1de533 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40b7ae552890e38ea81d2404b781c80d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3aafe599181ef96c1781f50d7dcd8f8d |
| publicationDate | 2015-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-094773-A1 |
| titleOfInvention | HETEROCYCLIC AMIDA COMPOSITE AND PHARMACEUTICAL COMPOSITION THAT INCLUDES IT |
| abstract | Claim 1: A heterocyclic amide compound characterized in that it has the formula (1), wherein: X is O, S, SO, SO₂, NH, CO, CH₂, CF₂, CH (CH₃), CH (OH) or N (CH₃); Y is CH₂ or CH₂CH₂; Z¹ is N, CH or CR¹; Z² is CH or CR²; Z³ is N, CH or CR³; Z⁴ is CH or CR⁴; R¹ is fluorine or methyl; one of R² and R³ is halogen, cyano, C₁₋₆ alkyl, C₁₋₄ haloalkyl, C₁₋₆ alkoxy, hydroxyl, B (OH) ₂, -COOH, C₁₋₄C₍OH₎₂- haloalkyl, C₁₋₄alkoxy alkoxy C₁₋₄, C₁₋₄SO₂- alkyl, C₁₋₄SO₂NHC (O) alkyl -, C₁₋₄C₍O₎NH₋ alkyl, ₍ₐₗqᵘⁱₗ C₁₋₄) (C₁₋₄ alkyl) NC (O) -, C₁₋ alkyl ₄OC (O) -, C₁₋₄C₍O₎N₋ₐₗqᵘⁱₗ C₁₋₄- alkyl, C₁₋₄NHC alkyl (O) -, C₁₋₄alkyl C₂₋₄NHC alkoxy (O) -, C₁₋₄alkyl C₂₋₄C₍ alkoxy O₎NH₋, ₐₗᶜₒˣⁱ C₁₋₄alkyl C₂₋₄NHC (O) NH-, alkyl C₁₋₄SO alqualkyl C₂₋₄NHC (O) -, alkyl C₁₋₄NHC (O) NH-, alkyl C₁₋₄OC (O) NH-, hydroxy-C₁₋₄OC alkyl (O) NH-, 5-6 membered heterocycloalkyl-C (O) -, 5-6 membered heterocycloalkyl-C₁₋₄-NHC alkyl (O) -, 5-6 membered heterocycloalkyl- C₁₋₄- alkoxy, 5-6 membered heteroaryl or 5-6 membered heteroaryl-C (O) NH, wherein said heterocyclic 5-6 membered alkyl and 5-6 membered heteroaryl are optionally substituted with 1 or 2 substituents each independently selected from the group consisting of C₁₋₄ alkyl and -C₁₋₄-CN alkyl; and the other of R² and R³ is halogen or C₁₋₆ alkyl; R⁴ is fluorine, chlorine or methyl; R⁵ is H or methyl; A is phenyl, 5-6 membered heteroaryl or 5-6 membered heterocycloalkyl, wherein the carbonyl moiety and L are substituted 1,3 in ring A; m is 0 or m is 1 and RA is C₁₋₄ alkyl; and L is O, S, NH, N (CH₃), CH₂, CH₂CH₂, CH (CH₃), CHF, CF₂, CH₂O, CH₂N (CH₃), CH₂NH or CH (OH); B is a C₃₋₆ cycloalkyl, phenyl, 5-6 membered heteroaryl or optionally substituted 5-6 membered heterocycloalkyl; wherein said C₃₋₆ cycloalkyl, phenyl, 5-6 membered heteroaryl or 5-6 membered heterocycloalkyl are unsubstituted or substituted with one or two substituents each independently selected from halogen, C₁₋₄ alkyl, C₁₋ haloalkyl ₄, C₁₋₄ alkoxy, C₁₋₄ haloalkoxy, nitro and C₁₋₄C₍O₎₋ alkyl; ₒ ₑₗ ʳₑₛₜₒ ₋L₋B ₑₛ ₐₗqᵘⁱₗₒ C₃₋₆, C₃₋₆ alkoxy, C₃₋₆ haloalkoxy, C₃₋₆ alkenyl or C₃₋₆ alkenyloxy; or a salt thereof. |
| priorityDate | 2013-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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