http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-094758-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e23523b6d87e7802077d03a866e07301 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d8c62833461f651b6de263b9463b3183 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 |
| filingDate | 2014-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4eff75e29738eddc35157f7a3a99a30e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cfdc249e343e29be1e45afd1af8feb5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6cf68ea8b1686db9b345eac9579dd90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_682328f57d0f52680f2f2d9e6dbd9ac4 |
| publicationDate | 2015-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-094758-A1 |
| titleOfInvention | TRANSDERMAL FORM OF CONTROLLED RELEASE FOR THE TREATMENT OF SKIN INJURIES |
| abstract | A transdermal form of controlled release for the treatment of skin lesions, which comprises an antibiotic of the fluoroquinolone family and a protease enzyme co-immobilized in a polymeric matrix of cryogel. Also, the present discloses a process for the preparation of said transdermal controlled release form for the treatment of skin lesions comprising the steps of: a) preparing a first aqueous solution comprising from 10 to 50% of (w / v ) of at least one hydrophilic polymer and 2.0-4.0% (w / v) of at least one polysaccharide, b) mixing the polymeric aqueous solution from step a) with an antibiotic of the fluoroquinolone family and a Protease enzyme to obtain a second aqueous solution, c) subject the second aqueous solution resulting from step b) to cycles of freezing (C) and thawing (D) at temperatures between -18 ° C to -25 ° C. Claim 3: A transdermal form according to claim 2, characterized in that said fluoroquinolone-derived antibiotic is enrofloxacin. Claim 13: A transdermal form according to claim 1, characterized in that said protease enzyme is a keratinase. |
| priorityDate | 2014-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.