http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-094693-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b8fae6bbf787fd922a88c105501e656f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-7023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-439 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-191 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4164 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4178 |
| filingDate | 2014-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac4362eb3f98bff597074651e0340c7c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_552aa5821343ffacf19feaf9ccb7a176 |
| publicationDate | 2015-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-094693-A1 |
| titleOfInvention | CHEMICAL COMPOSITIONS AND METHODS TO IMPROVE THE TRANSDERMAL SUPPLY OF THERAPEUTIC AGENTS |
| abstract | Chemical compositions and methods to improve transdermal penetration of therapeutic agents through the skin. Chemical compositions and methods may include combinations of a first fatty acid having about 14 or more carbon atoms and a second fatty acid having about 10 or less carbon atoms. These compositions are useful for the delivery of therapeutic agents, in particular difficult to deliver drugs, such as those having fused rings, including ondansetron, and large drugs such as peptides. These compositions may be formulated as transdermal gels, lotions, creams, transdermal patches, sprays or mists. Claim 1: A composition, characterized in that it comprises: a first fatty acid that is oleic acid, linolenic acid, linoleic acid, mystolic acid, palmitoleic acid, or erucic acid, or a derivative or congener thereof; and a second fatty acid that is 2-hydroxyoctanoic acid, 4-oxopentanoic acid, propionic acid, valeric acid, peruvian acid, acetoacetic acid, alanine, aspartic acid, asparagine, glutamic acid, glycine, licin, valine, or levulinic acid, or a derivative or congener of these. Claim 10: The composition of any one of claims 7 to 9, characterized in that the therapeutic agent is one or more of: ondansetron, dolasetron, granisetron, tropisetron, palonosetron, or salts thereof. Claim 21: The use of the composition according to any of claims 6 to 20 for the manufacture of a medicament for treating a disease or condition. Claim 34: A method of forming a composition, characterized in that it comprises mixing a first fatty acid that is oleic acid, linolenic acid, linoleic acid, myristoleic acid, palmitoleic acid, or erucic acid, or a derivative or congener thereof; with a second fatty acid that is 2-hydroxyoctanoic acid, 4-oxopentanoic acid, propionic acid, valeric acid, peruvian acid, acetoacetic acid, alanine, aspartic acid, asparagine, glutamic acid, glycine, licin, valine, or levulinic acid, or a derivative or congener of these; and a therapeutic agent. |
| priorityDate | 2012-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 79.