http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-094621-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37f4922dfb7777b019e504b885211b8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bcb35225a578542c5592310a91d18f18 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-708 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7105 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-708 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-10 |
| filingDate | 2011-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-094621-A1 |
| titleOfInvention | PHARMACEUTICAL COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF VIRAL INFECTIONS |
| abstract | Claim 1: A compound characterized by the formula (1), or a pharmaceutically acceptable stereoisomeric, tautomeric or polymorphic salt thereof, wherein: R is a portion that can be derived by removing a hydrogen from a hydroxy group of a antiviral drug, such as a nucleoside or nucleoside analog; X is O or S; Q is OR⁴, SR⁴ or NR⁵R⁶; each E is, independently, CR⁷R⁸; each n is 1 or 2; R¹ and R² are selected as follows: i) R¹ and R² are each, independently, hydrogen, alkyl, alkenyl, alkynyl, aryl, aralkyl, cycloalkyl, cycloalkenyl, alkylheterocyclyl or alkylheteroaryl; ii) R¹ and R², together with the nitrogen atom in which they are substituted, form a 3-7 membered heterocyclic or heteroaryl ring; or iii) R¹ is hydrogen, alkyl or cycloalkyl, and R² is (G) ₘC (O) Q¹, wherein Q¹ is OR⁴, SR⁴ or NR⁵R⁶; each G is, independently, CR⁷R⁸; and each m is 1 or 2; R³ and R⁴ are each, independently, hydrogen, alkyl, alkenyl, alkynyl, aryl, aralkyl, cycloalkyl or cycloalkenyl; R⁵ and R⁶ are selected as follows: i) R⁵ and R⁶ are each independently hydrogen, alkyl, alkenyl, alkynyl, aryl, aralkyl, cycloalkyl or cycloalkenyl; or ii) R⁵ and R⁶, together with the nitrogen atom in which they are substituted, form a 3-7 membered heterocyclic or heteroaryl ring; and R⁷ and R⁸ are selected in the following manner: i) R⁷ and R⁸ are each independently hydrogen, alkyl, alkenyl, alkynyl, aryl, aralkyl, cycloalkyl, cycloalkenyl, alkylheterocyclyl or alkylheteroaryl, wherein the alkyl is optionally substituted with alkoxy; or ii) R⁷ and R⁸, together with the carbon atom to which they are attached, form a 3-7 membered cycloalkyl ring; and where if R² is (G) ₘC (O) Q¹, G is CR⁷R⁸; m is 1, and one of R⁷ or R⁸ is hydrogen, the other of R⁷ and R⁸ is not methyl. |
| priorityDate | 2010-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.