| abstract |
Its preparation and its use as pharmaceutically active compounds. Claim 1: A compound of formula (1), wherein R¹ represents a heteroaryl or aryl group, wherein the groups are independently unsubstituted, mono-, di- or tri-substituted, wherein the substituents are independently selected from the group consisting in C₁₋₄ alkyl, C₃₋₆ cycloalkyl, C₁₋₄ alkoxy, C₁₋₃ fluoroalkyl, C₁₋₃ fluoroalkoxy, hydroxy, halogen and phenoxy; R² represents heterocyclyl, which is unsubstituted, mono- or di-substituted, wherein the substituents are independently selected from C₁₋₄ alkyl, C₁₋₄ alkylcarbonyl, C₁₋₄ alkoxycarbonyl, C₁₋₄ alkylsulfonyl and halogen; heterocyclyloxy; C₃₋₆ cycloalkyl, which is unsubstituted or mono- or di-substituted with halogen; C₃₋₆ cycloalkyloxy; N-cycloalkyl C₃₋₆-amino; N-cycloalkyl C₃₋₆-methyl-amino; C₃₋₆ alkyl; C₂₋₆ alkoxy; N-Cila alkylamino; N, N-di- [C₁₋₄ alkyl] -amino; or N-arylmethyl-N-C₁₋₄-alkyl alkyl; R³ represents hydrogen or halogen; R⁴ represents hydrogen, fluoro, chloro, C₁₋₄ alkyl, C₁₋₄ alkoxy, C₁₋₄ alkylcarbonyl, hydroxyC₁₋₄ alkyl, hydroxyC₂₋₄ alkoxy, C₁₋₂ alkoxy-C₁₋₄ alkyl or alkoxy C₁₋₄-C₂₋₄ alkoxy; R⁵ represents hydrogen or C₁₋₄ alkyl; and R⁶ represents fluoro, chloro, methyl, ethyl or C₁₋₂ fluoroalkyl; or a salt of said compound. |