| abstract |
Claim 1: A compound of formula (1) or an N-oxide thereof, or a pharmaceutically acceptable salt, solvate, polymorph or tautomer of said compound of formula (1) or N-oxide thereof, wherein Z is (CRᵃRᵇ ) ₚN (Rᵃ) (CRᵃRᵇ) q; X¹ and X² are each independently selected from halo and OSO₂Rᶜ; P is a compound of the formula (2); Q is heteroaryl, which is optionally substituted with alkyl, alkenyl, alkynyl, cycloalkyl, halo, nitro, oxo, cyano or ORᵉ; Rᵃ, Rᵇ, Rᵈ and Rᵉ are each independently selected from H, alkyl, alkenyl and alkynyl; Rᶜ is selected from alkyl, alkenyl and alkynyl; and p and q are each independently selected from 0, 1, 2, 3 and 4. |