abstract |
This refers to mGlu2 / 3 agonists useful in the treatment of neurological or psychiatric disorders. Claim 1: A compound of formula (1) characterized in that R¹ is hydrogen, R² is hydrogen, and R³ is hydrogen; R¹ is hydrogen, R² is (2S) -2-aminopropanoyl, and R³ is hydrogen; R¹ is hydrogen, R² is (2S) -2-amino-4-methylsulfanyl-butanoyl, and R³ is hydrogen; R¹ is hydrogen, R² is 2-aminoacetyl, and R³ is hydrogen; R¹ is benzyl, R² is hydrogen, and R³ is benzyl; or R¹ is (2-fluorophenyl) methyl, R² is hydrogen, and R³ is (2-fluorophenyl) methyl; or a pharmaceutically acceptable salt thereof. |