http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-088461-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7d3c8c72f38e8b49a945a43ce4c39ebd |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C381-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-277 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-277 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-00 |
| filingDate | 2012-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46e58406e1aa808b1ff1b27d00b608eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6c02f72e0361a798a93f04e44228062 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3f394f33b91017aa81005c2b9a4cbd2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57b3fa6ad65aa842f1de37d390a16ea8 |
| publicationDate | 2014-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-088461-A1 |
| titleOfInvention | USE OF AMINOACETONITRILE DERIVATIVES AGAINST ENDOPARASITES |
| abstract | Claim 1: A method for treating an endoparasitic infection caused by filariae in an animal that needs it, characterized in that it comprises administering to the animal an effective amount of a compound of the formula (1), a stereoisomer or a salt thereof acceptable in veterinary medicine in where: R¹, R², R³, R⁴ and R⁵ are each independently selected from H, halo, CN, CF₃, methyl, methoxy, -OCF₃ and -SCH₃, wherein the compound is effective in treating endoparasitic infection. Claim 3: The method according to claim 2, characterized in that the compound of the formula (1) is selected from the group consisting of: N- {1-cyano-2- [3-cyano-5- (trifluoromethyl) phenoxy ] -methylethi} -4- (pentafluoroth) -benzamide; N- [2- (2-Bromo-5-cyanophenoxy) -1-cyano-1-methylethi] -4- (pentafluorothium) -benzamide; and @@@ N - {(1S) 1-cyano-2- [4-cyano-2- (trifluoromethyl) phenoxy] -1-methylethyl} -4-pentafluorothiobenzamide, a stereoisomer thereof, or a salt of the acceptable compound in veterinary or a stereoisomer of this. Claim 4: A method of treating an endoparasitic infection caused by filariae in an animal that needs it, characterized in that it comprises administering to the animal an effective amount of a compound of the formula (2), a stereoisomer or a salt thereof acceptable in veterinary medicine, wherein: where R¹ᵃ, R¹ᵇ, R¹ᶜ, R¹ᵈ and R¹ᵉ are each independently selected from the group consisting of hydrogen, halo, CF₃, -OCH₃, methyl and hydroxyl. Claim 15: A compound characterized in that it is selected from the group consisting of: N- {1-cyano-2- [5-cyano-2- (4-fluorophenoxy) phenoxy] -1-methylethi} -4- (pentafluorothium) benzamide ; N- {2- [2- (4-Chloro-2-fluorophenoxy) -5-cyanophenoxy] -1-cyano-1-methylethyl) -4- (pentafluorothium) benzamide; N- {2- [2- (4-chlorophenoxy) -5-cyanophenoxy] -1-cyano-1-methylethyl} -4- (pentafluorothium) benzamide; N- (1-Cyano-2- {5-cyano-2- [4- (trifluoromethyl) phenoxy] phenoxy} -1-methylethyl) -4- (pentafluorothium) benzamide. N- {2- [2- (2-Chloro-4-methylphenoxy) -5-cyanophenoxy] -1-cyano-1-methylethyl} -4- (pentafluorothium) benzamide; N- {1-cyano-2- [5-cyano-2- (2,4-dimethylphenoxy) phenoxy] -1-methylethyl} -4- (pentafluorothium) benzamide and N- {1-cyano-2- [5- cyano-2- (3,5-difIuoro-4-methoxyphenoxy) phenoxy] -1-methylethyl} -4- (pentafluorothium) benzamide, stereoisomers and salts thereof acceptable in veterinary or pharmacy. |
| priorityDate | 2011-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.