http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-087607-A1

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filingDate 2012-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2014-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber AR-087607-A1
titleOfInvention DERIVATIVES OF PIRIDAZINONA
abstract The processes for their preparation, the pharmaceutical compositions that contain them and their use in therapy. Claim 1: A compound of formula (1) wherein R¹ represents a hydrogen or fluorine atom or a trifluoromethyl group; R² represents a group -X-Y-R³; X and Y each independently represent a bond, an oxygen atom or a group -C (O), -S (O) ₙ, -C (O) NR⁴, -S (O) ₂NR⁴, -NR⁴, a remainder of formula (2) or (3), or -CR⁴R⁵-, provided that X and Y cannot both simultaneously represent a link and provided that if X and Y are both different from a link, then at least one of X and Y represents - CR⁴R⁵-; n is 0, 1 or 2; each R⁴ independently represents a hydrogen atom or a C₁₋₆ alkyl or C₁₋₆ haloalkyl group; each R⁵ independently represents a hydrogen atom, a C₁₋₆ alkyl or C₁₋₆ or = CH- haloalkyl group; R³ represents a saturated or unsaturated carbocyclic or heterocyclic ring system of 3 to 10 members, the ring system itself is optionally substituted by at least one substituent selected from halogen, hydroxyl, cyano, oxo, C₁₋₆ alkyl, C₂ alkenyl ₋₆, C₁₋₆ haloalkyl, C₁₋₆ hydroxyalkyl, C₁₋₆ alkoxy, C₁₋₆ haloalkoxy, C₁₋₆ alkylthio, C₁₋₆ alkylsulfinyl, C₁₋₆ alkylsulfonyl, C₁₋₆ alkylcarbonyl, C₁₋₆ alkylcarbonyloxy, C₁ alkoxycarbonyl ₋₆, amino (-NH₂), -CON (R⁶) ₂, C alqu alkylamino, C₁₋₆ dialkylamino, C₃₋₆ cycloalkyl, C₃₋₆ cycloalkyloxy, C₃₋₆ cycloalkylmethyl, - [O] ₚ- (CH₂) qO-R⁷ and a saturated or unsaturated 4 to 6 membered heterocyclic ring (optionally substituted with at least one substituent selected from C₁₋₄ alkyl and C₁₋₄ alkoxy); each R⁶ independently represents a hydrogen atom or a C₁₋₆ alkyl group; p is 0 or 1; q is 1, 2, 3 or 4; and R⁷ represents a C₁₋₆ alkyl group; or a pharmaceutically acceptable salt thereof.
priorityDate 2011-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 44.