http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-087607-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_28e3113097dd6d28720572e47f2f2407 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D407-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-501 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D237-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D237-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D237-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D237-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-0812 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D407-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D237-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-501 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-10 |
filingDate | 2012-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2014-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | AR-087607-A1 |
titleOfInvention | DERIVATIVES OF PIRIDAZINONA |
abstract | The processes for their preparation, the pharmaceutical compositions that contain them and their use in therapy. Claim 1: A compound of formula (1) wherein R¹ represents a hydrogen or fluorine atom or a trifluoromethyl group; R² represents a group -X-Y-R³; X and Y each independently represent a bond, an oxygen atom or a group -C (O), -S (O) ₙ, -C (O) NR⁴, -S (O) ₂NR⁴, -NR⁴, a remainder of formula (2) or (3), or -CR⁴R⁵-, provided that X and Y cannot both simultaneously represent a link and provided that if X and Y are both different from a link, then at least one of X and Y represents - CR⁴R⁵-; n is 0, 1 or 2; each R⁴ independently represents a hydrogen atom or a C₁₋₆ alkyl or C₁₋₆ haloalkyl group; each R⁵ independently represents a hydrogen atom, a C₁₋₆ alkyl or C₁₋₆ or = CH- haloalkyl group; R³ represents a saturated or unsaturated carbocyclic or heterocyclic ring system of 3 to 10 members, the ring system itself is optionally substituted by at least one substituent selected from halogen, hydroxyl, cyano, oxo, C₁₋₆ alkyl, C₂ alkenyl ₋₆, C₁₋₆ haloalkyl, C₁₋₆ hydroxyalkyl, C₁₋₆ alkoxy, C₁₋₆ haloalkoxy, C₁₋₆ alkylthio, C₁₋₆ alkylsulfinyl, C₁₋₆ alkylsulfonyl, C₁₋₆ alkylcarbonyl, C₁₋₆ alkylcarbonyloxy, C₁ alkoxycarbonyl ₋₆, amino (-NH₂), -CON (R⁶) ₂, C alqu alkylamino, C₁₋₆ dialkylamino, C₃₋₆ cycloalkyl, C₃₋₆ cycloalkyloxy, C₃₋₆ cycloalkylmethyl, - [O] ₚ- (CH₂) qO-R⁷ and a saturated or unsaturated 4 to 6 membered heterocyclic ring (optionally substituted with at least one substituent selected from C₁₋₄ alkyl and C₁₋₄ alkoxy); each R⁶ independently represents a hydrogen atom or a C₁₋₆ alkyl group; p is 0 or 1; q is 1, 2, 3 or 4; and R⁷ represents a C₁₋₆ alkyl group; or a pharmaceutically acceptable salt thereof. |
priorityDate | 2011-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.