http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-087148-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_96ec3985e3ce9b24614fb87bf51a4f12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1f67dd95fb433cb3458c52756dbd5b4c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5025 |
| filingDate | 2012-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_235d413b915716b745c4e31559ec0a72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6a59da9234175359256b4729717bee0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0611ba606faf3c245b7ec35ecb791c1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6933c5171969abbf6703d8f88cacc16a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_082e317997a32bd93671298720e0de26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d5de5c8aa8578f4c0883c0cae0d9f5c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0045b210fa5e6506b9a48478ae1d4624 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73c8efe46b737ebcb9d2ea68d1326653 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9830968e484d90daef598bbff5ab86ec |
| publicationDate | 2014-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-087148-A1 |
| titleOfInvention | IMIDAZOPIRIDAZINAS |
| abstract | Compounds useful for the treatment of diseases related to deregulated cell proliferation. Claim 1: A compound of formula (1), wherein R1 is hydrogen, hydroxy, NR5R6, halogen, cyano, CO (NR8R9), C (O) OR8 , C (O) (C1-6 alkyl), NHC (O) (C1-6 alkyl), NHS (O) 2R11, NHC (O) NHR11, -S (O) n-C1-6 alkyl, -S ( O) 2NR5R6 or a group selected from C 1-6 alkyl, C 1-6 alkoxy, C 3-7 cycloalkyl, aryl, heteroaryl, - (C 1-6 alkyl) -aryl, - (C 1-6 alkyl) -heteroaryl, -O- (C3-7 cycloalkyl), -O-aryl, -O- (C3-7 heterocyclyl), -O-heteroaryl, -O- (C1-6 alkyl) -heteroaryl, -O- (C1-6 alkyl) - ( C3-7 heterocyclyl), -O- (C1-6 alkyl) -aryl, C2-6 alkenyl, C2-6 alkynyl, wherein said group is optionally substituted, one or more times, identically or differently, with a substituent selected Among: hydroxy, halogen, C1-6 alkyl, C1-4 haloalkyl, C1-6 alkoxy, -NR8R9, cyano, -C (O) NR8R9, -C (O) OR10, -NHC (O) R11, -NHC ( O) NHR11, -NHS (O) 2R11, C3-7 cycloalkyl, heterocyclic C3-7 lilo, aryl; R2 is hydrogen, hydroxy, NR5R6, halogen, cyano, CO (NR8R9), C (O) OR8, C (O) (C1-6 alkyl), NHC (C1-6 alkyl), NHS (O) 2R11, NHC ( O) NHR11, -S (O) n-C1-6 alkyl, -S (O) 2NR5R6 or a group selected from C1-6 alkyl, C1-6 alkoxy, C3-7 cycloalkyl, aryl, heteroaryl, - (C1 alkyl -6) -aryl, - (C1-6 alkyl) -heteroaryl, -O- (C3-7 cycloalkyl), -O-aryl, -O- (C3-7 heterocyclyl), -O-heteroaryl, -O- ( C1-6 alkyl) -heteroaryl, -O- (C1-6 alkyl) - (C3-7 heterocyclyl), -O- (C1-6 alkyl) -aryl, C2-6 alkenyl, C2-6 alkynyl, wherein said group is optionally substituted, one or more times, identically or differently, with a substituent selected from: hydroxy, halogen, C1-6 alkyl, C1-4 haloalkyl, C1-6 alkoxy, -NR8R9, cyano, -C (O) NR8R9, -C (O) OR10, -NHC (O) R11, -NHC (O) NHR11, -NHS (O) 2R11, C3-7 heterocyclyl, aryl; R3 is hydrogen, hydroxy, NR5R6, halogen, cyano, CO (NR8R9), C (O) OR8, C (O) (C1-6 alkyl), NHS (O) 2R11, NHC (O) NHR11, -S (O ) n-C1-6 alkyl, -S (O) 2NR5R6 or a group selected from C1-6 alkyl, C1-6 alkoxy, C3-7 cycloalkyl, aryl, heteroaryl, (C1-6 alkyl) -aryl, - (alkyl C1-6) -heteroaryl, -O- (C3-7 cycloalkyl), -O-aryl, -O- (C3-7 heterocyclyl), -O-heteroaryl, -O- (C1-6 alkyl) -heteroaryl, - O- (C1-6 alkyl) - (C3-7 heterocyclyl), -O- (C1-6 alkyl) -aryl, NHC (O) (C1-6 alkyl), C2-6 alkenyl, C2-6 alkynyl, where said group is optionally substituted, one or more times, identically or differently, with a substituent selected from: hydroxy, halogen, C1-6 alkyl, C1-4 haloalkyl, C1-6 alkoxy, -NR8R9, cyano, -C ( O) NR8R9, -C (O) OR10, -NHC (O) R11, -NHC (O) NHR11, -NHS (O) 2R11, C3-7 heterocyclyl, aryl; R4 is phenyl which is optionally substituted once, twice or three times, identically or differently, with a halogen atom; R5 is hydrogen, C1-6 alkyl; R6 is hydrogen, C1-6 alkyl; R8 is hydrogen, C1-6 alkyl which is optionally substituted with hydroxy; R9 is hydrogen, C1-6 alkyl; R10 is hydrogen, C1-6 alkyl; R11 is hydrogen, C1-6 alkyl; X, Y is CH2; n is 0, 1, 2; or an N-oxide, a salt, a tautomer or a stereoisomer of said compound, or a salt of said N-oxide, tautomer or stereoisomer. |
| priorityDate | 2011-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.