| abstract |
Claim 1: A pharmaceutical composition in the form of rapidly dissolving vaginal administration microgranules that includes: (a) a therapeutically effective amount of a vaginally active drug; (b) a polymeric excipient with the dual property of acting as a binder, as well as as a bioadhesive material; (c) a sugar alcohol, a saccharide or a combination thereof; and (d) a disintegrant; where the pharmaceutical composition disintegrates rapidly after insertion into the vaginal cavity of a patient or subject and forms a viscous suspension containing the drug that spreads rapidly and widely and covers the vaginal mucosa. |