http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-086043-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_116c851e729089df9a427027272fa290 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2440-14 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-566 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-573 |
| filingDate | 2012-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2013-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-086043-A1 |
| titleOfInvention | TEST SYSTEM AND METHODS TO IDENTIFY A COMPOUND THAT ALTERS THE CELLULAR ACTIVITY OF THE DDR |
| abstract | Claim 1: An assay system for determining the auto- / transfosphorylation activity of the collagen-induced discoidine domain (DDR) receptor, comprising: a) at least one cell containing at least one DDR polypeptide or a functional derivative of the same located in the plasma membrane of the cell, b) any of b1) or b2): b1) a binding partner capable of selectively recognizing phosphotyrosine, said binding partner being a labeled binding partner, b2) a binding partner capable of selectively recognizing phosphotyrosine and another binding partner, which is a labeled binding partner, and which is capable of selectively recognizing the binding partner that recognizes phosphotyrosine, c) at least one reagent to fix the cells to a support solid and permeabilize them, d) at least one solid support to fix the cells and to cultivate them, e) at least one collagen, f) optionally, at least one compound It is suspected that it alters the collagen-induced auto- / transfosphorylation of at least one DDR polypeptide or a functional derivative thereof, and g) means for detecting the binding partner of b) or c). |
| priorityDate | 2011-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.