http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-085185-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5999a169b4a808f92bf78c30d997d963 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_29ece69a4c874f32c2cb8c8fa746255a |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 |
filingDate | 2011-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d530db6407a1e29cc87fdfe3131bcc1b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08b7ef5791497869746b9656da9f9325 |
publicationDate | 2013-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | AR-085185-A1 |
titleOfInvention | A PHARMACEUTICAL COMPOSITION OF DUAL PROGRAMMED ACTION, 6- [4- (1-CICLOHEXIL-1H-TETRAZOL-5-IL) BUTOXI] -3,4-DIHYDRO-2 (1H) -CHINOLINONE (CYLOSTAZOL), MANUFACTURING PROCEDURE |
abstract | An orally administered pharmaceutical composition of programmed action for dual release, comprising 6- [4- (1-cyclohexyl-1H-tetrazol-5-yl) butoxy] -3,4-dihydro-2 (1H) -quinolinone ( Cilostazol) in the form of pellets, spherical units or microgranules of immediate release in combination with pellets, spherical units or microgranules of controlled release. A process for preparing said pharmaceutical composition. A method of treatment of peripheral vasculopathies, ischemic syndrome of the lower limbs due to chronic occlusive arterial disease (intermittent claudication), pain, ulcers, trophic disorders, paraesthesia, cold sensation, secondary prevention after revascularization procedures, which consists of administer a dose unit comprising between 10 mg and 500 mg, preferably between 20 mg and 300 mg, more preferably between 25 mg and 250 mg, of the active substance. The use of the combination of pellets, spherical units or microgranules for the manufacture of a medicament for the treatment of peripheral vasculopathies, ischemic syndrome of the lower limbs due to chronic occlusive arterial disease (intermittent claudication), pain, ulcers, trophic disorders, paraesthesia, cold sensation, secondary prevention after revascularization procedures. |
priorityDate | 2011-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.