http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-084864-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_938a6d7a15cbc93a74abe1953eb25d47 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 |
filingDate | 2012-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c57318a7170ff1b5c53448088bada85d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a54e227c2e7200e6ec0e9096a6dad13e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25bca36cd96436a35e091ffa5f0e5113 |
publicationDate | 2013-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | AR-084864-A1 |
titleOfInvention | PROCESS FOR PREPARATION OF GIRASA AND INHIBITORS OF TOPOISOMERASE IV AND INTERMEDIATE COMPOUNDS OF SUCH PROCESS |
abstract | Claim 1: A method for the preparation of a compound of formula (1) or a pharmaceutically acceptable salt thereof, wherein R is H or F; and each of R3, R4, and R5 is independently an optionally substituted alkyl, or an optionally protected hydroxyl group: comprising the provision of a phenylpyrimidine compound of formula (2) wherein R is H or F, and each of R3, R4 and R5 is independently an optionally substituted alkyl or an optionally protected hydroxyl group; and the reaction of the phenylpyrimidine compound of formula (2) with a urea derivative of formula (3) or (4), wherein R 6 is an optionally substituted alkyl, an optionally substituted aryl, an unsaturated or optionally substituted saturated carbocycle, or an unsaturated or saturated heterocycle optionally substituted to provide a compound of formula (1); and partially reacting the compound of formula (1) with a suitable acid to provide a pharmaceutically acceptable salt of the compound of formula (1). |
priorityDate | 2011-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID458397310 |
Total number of triples: 22.