http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-084353-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ddccfe62e94cf3f781ac2b8220582da1 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-416 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-416 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 2011-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abfc029d41137b549585d61262cc2e34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c65efc13e9ee83c4a3bab24993400b10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aee944c22c38acc2ae21c3d7060eef02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06cce7cbc3316a6e2290cd59a5c7b428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f999781c96a16bf2e57138fa2f8ed4e8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5156fcf081ac01545990e3c11a4b4277 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3bd235f1a2b10c40bff82fbce5ea6e6e |
| publicationDate | 2013-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-084353-A1 |
| titleOfInvention | TRICYCLES OF PIRAZOLILO AND PIRIMIDINILO USEFUL AS ANTI-INFLAMMATORY AND / OR ANTIOXIDANT AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| abstract | Claim 1: A compound of the formula: (1), atoms labeled 1 and 2 are connected through a double bond or an epoxidized double bond; n is 1 or 2; m is 0 or 1; X is -CN, -CF3, or -C (O) Ra, where Ra is -OH, C 6 alkoxy, C 6 alkylamino, C 6 dialkylamino, or -NHS (O) 2-C 1-4 alkyl; R1 and R2 are independently hydrogen, hydroxy, halo, or amino; or C 12 alkyl, C 12 alkenyl, C 12 alkynyl, C 12 aryl, C 12 aralkyl, C 12 heteroaryl, C 12 heterocycloalkyl, C 12 acyl, C 12 alkoxy, C 12 aryloxy , C £ 12 aralkoxy, C 12 heteroaryloxy, C 12 acyloxy, C 12 alkylamino, C 12 dialkylamino, C 12 arylamino, C 12 alkylamino C, 12 C heteroarylamino, C 12 amido, or a substituted version of any of these groups; or R 1 and R 2 are taken together and are C 12 alkanyl, C 12 alkenyl, C 12 alkoxyidiyl, C 12 alkylaminodiyl, or a substituted version of any of these groups; R3 is null, hydrogen; or C 12 alkyl, C 12 alkenyl, C 12 alkynyl, C 12 aryl, C 12 aralkyl, C 12 heteroaryl, C 12 heterocycloalkyl, C 12 acyl or a substituted version of any of these groups; or R3 is taken together with R4 as described below; with the proviso that R3 is absent only when the atom to which it is attached is part of a double bond; R4 is hydrogen, hydroxy, amino, halo, cyano, or oxo; or C 12 alkyl, C 12 alkenyl, C 12 alkynyl, C 12 aryl, C 12 aralkyl, C 12 heteroaryl, C 12 heterocycloalkyl, C 12 acyl, C 12 alkoxy, C 12 aryloxy , C £ 12 aralkoxy, C 12 heteroaryloxy, C 12 acyloxy, C 12 alkylamino, C 12 dialkylamino, C 12 arylamino, C 12 alkylamino C, 12 C heteroarylamino, C 12 amido, or a substituted version of any of these groups; or R4 is taken together with R3 or R5 as described below; R5 is null, hydrogen; or C 12 alkyl, C 12 alkenyl, C 12 alkynyl, C 12 aryl, C 12 aralkyl, C 12 heteroaryl, C 12 heterocycloalkyl, C 12 acyl or a substituted version of any of these groups; or R5 is taken together with R4 as described below; with the proviso that R5 is absent only when the atom to which it is attached is part of a double bond; and R6 is hydrogen, hydroxy, amino, halo, cyano, or oxo; or C 12 alkyl, C 12 alkenyl, C 12 alkynyl, C 12 aryl, C 12 aralkyl, C 12 heteroaryl, C 12 heterocycloalkyl, C 12 acyl, C 12 alkoxy, C 12 aryloxy , C £ 12 aralkoxy, C 12 heteroaryloxy, C 12 acyloxy, C 12 alkylamino, C 12 dialkylamino, C 12 arylamino, C 12 alkylamino C 12, C 12 heteroarylamino, C 12 amido, or a substituted version of any of these groups; with the proviso that when R3 and R4 are taken together, the compound is further defined by means of formula (2) where R7 is hydrogen, hydroxy, amino, halo, or cyano; or C 12 alkyl, C 12 alkenyl, C 12 alkynyl, C 12 aryl, C 12 alkyl, C 12 heteroaryl, C 12 heterocycloalkyl, C 12 acyl, C 12 alkoxy, C 12 aryloxy , C £ 12 aralkoxy, C 12 heteroaryloxy, C 12 acyloxy, C 12 alkylamino, C 12 dialkylamino, C 12 arylamino, C 12 alkylamino C, 12 C heteroarylamino, C 12 amido, or a substituted version of any of these groups; or with the proviso that when R4 and R5 are taken together, the compound is further defined by means of formula (3) where R8 is hydrogen, hydroxy, amino, halo, or cyano; or C 12 alkyl, C 12 alkenyl, C 12 alkynyl, C 12 aryl, C 12 aralkyl, C 12 heteroaryl, C 12 heterocycloalkyl, C 12 acyl, C 12 alkoxy, C 12 aryloxy , C £ 12 aralkoxy, C 12 heteroaryloxy, C 12 acyloxy, C 12 alkylamino, C 12 dialkylamino, C 12 arylamino, C 12 alkylamino C, 12 C heteroarylamino, C 12 amido, or a substituted version of any of these groups; or a pharmaceutically acceptable salt or tautomer thereof. |
| priorityDate | 2010-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 43.