http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-082698-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_28e3113097dd6d28720572e47f2f2407 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 |
| filingDate | 2011-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_538999383276b26e1328e7259cef02ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70f60777c5324fe266eea6f76ca33d6b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b950de9bee79efe53e7f96a9fc9e13f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fe19422bda6d0aa58d54585466325aa |
| publicationDate | 2012-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-082698-A1 |
| titleOfInvention | USEFUL TIENOPIRIMIDINE DERIVATIVES FOR CANCER TREATMENT |
| abstract | It is useful for the prevention or treatment of cancer. Claim 1: A compound represented by the formula (1) characterized in that one of X and Y is a sulfur atom and the other is CH; R1 is a C1-6 alkyl group optionally substituted with halogen atoms; R2 is a substituent; or one of its salts. Claim 4: The compound according to claim 1, characterized in that R2 is (I) a C1-6 alkyl group optionally substituted with 1 to 3 substituents selected from (a) a non-aromatic heterocyclic group optionally substituted with 1 to 3 substituents selected of (i) a halogen atom, (ii) a hydroxy group, (iii) a C1-6 alkyl group optionally substituted with 1 to 3 substituents selected from (aa) a halogen atom, (bb) a hydroxy group, ( cc) a C1-6 alkoxy group and (dd) a C6-14 aryl group optionally substituted with 1 to 3 C1-6 alkyl groups, (iv) a C1-6 alkoxy group, (v) a C6-14 aryl group optionally substituted with 1 to 3 halogen atoms, (vi) a C6-14-oxy aryl group, (vii) a C1-6 alkoxycarbonyl group, (viii) a C1-6 alkylcarbonyl group, (ix) a group cyano, (x) a C6-14-sulfonyl aryl group, (xi) a carboxy group, (xii) an optionally mono- or disubstituted amino group with a C1-6 alkyl group, (xiii) a het group non-aromatic erocyclic optionally substituted with an oxo group and (xiv) an oxo group, (b) a C1-6 alkoxy group, (c) an optionally mono- or disubstituted amino group with substituents (s) selected from (i) a group C1-6 alkyl optionally substituted with 1 to 3 substituents selected from (aa) a C6-14 aryl group optionally substituted with 1 to 3 C1-6 alkoxy groups, (bb) a C1-6 alkoxycarbonyl group, (cc) a aromatic heterocyclic group, (dd) a C3-8 cycloalkyl group optionally substituted with an aromatic heterocyclic group and (ee) a hydroxy group, (ii) a non-aromatic heterocyclic group optionally substituted with 1 to 3 C7-13 aralkyl groups, (iii ) a C6-14 aryl group optionally substituted with 1 to 3 C1-6 alkoxy groups and (iv) a C3-8 cycloalkyl group, (d) a 5- or 6-membered aromatic heterocyclic group, (e) a C6- aryl group 14 and (f) a C3-8 cycloalkyl group optionally substituted with an amino group; (II) a C6-14 aryl group optionally substituted with 1 to 3 halogen atoms; (III) a non-aromatic heterocyclic group optionally substituted with 1 to 3 substituents selected from (a) a halogen atom, (b) a C1-6 alkyl group optionally substituted with 1 to 3 substituents selected from (i) a hydroxy group, (ii) a C1-6 alkoxycarbonyl group and (iii) a carbamoyl group, (c) a C6-14-oxy aryl group, (d) a C1-6 alkoxycarbonyl group, (e) a C1 alkyl group -6-carbonyl, (f) a C6-14 aryl group optionally substituted with a C1-6 alkyl sulfonyl group, (g) a C7-13 aralkyl group optionally substituted with 1 to 3 halogen atoms, (h) a group hydroxy, (i) a carbamoyl group and (j) a non-aromatic heterocyclic group; (IV) a C2-6 alkenyl group optionally substituted with 1 to 3 C6-14 aryl groups; (V) a 5- or 6-membered aromatic heterocyclic group; (VI) a non-aromatic heterocyclyl carbonyl group; or (VII) a C3-8 cycloalkyl group optionally substituted with an amino group or a salt thereof. |
| priorityDate | 2011-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 21.