Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a5ffa3f9d6b87e15e0a1551fb129b531 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B65B7-285 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-124 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M15-009 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B65B31-003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B65B3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-16 |
filingDate |
2010-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c31b20a95be0859d45cdf29fe6617d7a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8135cedd3302c1d86007b215091751c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd955db00849d42868e18123d7f20afb |
publicationDate |
2012-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
AR-079726-A1 |
titleOfInvention |
COMBINED THERAPY FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD). COMPOSITION FARMACEUTICA.FRASCO DE AEROSOL. METHOD COMPONENT ASSEMBLY |
abstract |
Aerosol formulation that is suitable for administration to patients with chronic obstructive pulmonary disease (COPD) by means of a pressurized metered dose inhaler (pMDI), which comprises glycopyrronium bromide in combination with formoterol. The formulation further comprises an HFA propellant, a cosolvent, and an amount of inorganic acid that is sufficient to stabilize both the glycopyrronium bromide component and that of formoterol. Optionally the formulation further comprises beclomethasone dipropionate. Spray bottle. Method to refill the bottle. Component set Claim 1: A pharmaceutical composition characterized in that it comprises: (a) glycopyrronium bromide; and (b) formoterol or a salt thereof; dissolved in an HFA propellant and a cosolvent, characterized in that said composition contains an amount of 1 M HCI in the range between 0.1 and 0.3 micrograms / microliter. |
priorityDate |
2009-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |