http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-075935-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f834ce5e3653300cfeee6fc9f68468f7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-498 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 |
| filingDate | 2010-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef179148d930e338e6b54d981e88ba3b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe4c656eb6e751be5c51d2e193a771d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6fda843b2431771218c80e0814c509a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_762d448965b097cfcf56c62389fa7619 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9d469e25b25305f43defbfe477456ee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ddfa699c4ec996fcfd1daca49509d4ea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e980f0e7a63117ae740658936c938a10 |
| publicationDate | 2011-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-075935-A1 |
| titleOfInvention | DERIVATIVES OF QUINOXALINE AND ITS USE FOR THE TREATMENT OF BENIGN AND EVIL TUMORS |
| abstract | Claim 1: Quinoxaline derivatives characterized in that they have the general formula 1 in which X is: oxygen or sulfur; R1 is hydrogen, substituted or unsubstituted C1-12 alkyl, cyano, halogen, R2 / R3 are hydrogen, substituted or unsubstituted C1-12 alkyl, R4 is hydrogen, substituted or unsubstituted C1-12 alkyl, unsubstituted or substituted cycloalkyl , unsubstituted or substituted heterocyclyl, unsubstituted or substituted aryl, unsubstituted or substituted heteroaryl, unsubstituted or substituted alkylaryl, unsubstituted or substituted alkylheteroaryl, and R5-R8 are hydrogen, substituted or unsubstituted C1-12 alkyl, unsubstituted aryl or substituted, unsubstituted or substituted heteroaryl, halogen, cyano, hydroxyl, C1-12 alkoxy, amino, carboxyl, alkoxycarbonyl, carboxyalkyl or alkoxycarbonylalkyl, alkoxycarbonylamino, alkoxycarbonylaminoalkyl, and with the proviso that at least one of the R5-R8 substituents is an unsubstituted or substituted aryl or radical heteroaryl, and where the substituents are selected from the group consisting of F, Cl, Br, I, CN, CF3, NH2, NH-alkyl, NH-aryl, N (al chyl) 2, NH-CO-alkyl, NH-CO-aryl, NH-CO-heteroaryl, NH-SO2-alkyl, NH-SO2-aryl, NH-SO2-heteroaryl, NH-CO-NH-alkyl, NH- CO-NH-aryl, NH-CO-NH-heteroaryl, NH-C (O) O-alkyl, NH-C (O) O-aryl, NH-C (O) O-heteroaryl, NO2, SH, S- alkyl, OH, OCF3, O-alkyl, O-aryl, O-CO-alkyl, O-CO-aryl, O-CO-heteroaryl, OC (O) O-alkyl, OC (O) O-aryl, OC ( O) O-heteroaryl, O-CO-NH-alkyl, O-CO-N (alkyl) 2, O-CO-NH-aryl, O-CO-NH-heteroaryl, OSO3H, OSO2-alkyl, OSO2-aryl, OSO2-heteroaryl, OP (O) OH) 2, alkyl-P (O) (OH) 2CHO, CO2H, C (O) O-alkyl, C (O) O-aryl, C (O) O-heteroaryl, CO -alkyl, CO-aryl, CO-heteroaryl, SO3H, SO2-NH2, SO2-NH-alkyl, SO2-NH-aryl, SO2-NH-heteroaryl, alkyl, cycloalkyl, heterocyclyl, aryl and heteroaryl, where the alkyl alkyl radicals, "Cycloalkyl", "heterocyclyl", "aryl" and "heteroaryl" may also be substituted, their physiologically acceptable salts, hydrates and solvates, where the compounds of the general formula (1) and their salts, hydrates or solv Atos may be present in the form of their racemates, enantiomers and / or diastereomers, or in the form of mixtures of their enantiomers and / or diastereomers, in the form of tautomers and their polymorphic forms. |
| priorityDate | 2009-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.