http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-075812-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d9cf7ff1f08310f0557c06b9a0f910a9 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| filingDate | 2010-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0bc99a821ee9b42ff300980b01c5b979 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a45c5b0e838739da37c1ea1034b9b409 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33fd454aa8e1dd7cd8316a705ca540a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc99776e5ea322d90a0c03605950801a |
| publicationDate | 2011-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-075812-A1 |
| titleOfInvention | PIRROL DERIVATIVES [2,3-B] PIRIDINE AS RAF QUINASA INHIBITORS |
| abstract | Propan-1 acid {2,4-difluoro-3- [5- (2-methoxy-pyrimidin-5-yl) -1H-pyrrole [2,3-b] pyridin-3-carbonyl-phenyl} -amide compounds sulfonic acid, propan-1-sulfonic acid [3- (5-cyano-1H-pyrrole [2,3b] pyridin-3-carbonyl) -2,4-difluoro-phenyl] -amide, [3- (5- Propan-1-sulfonic acid cyano-1H-pyrrole [2,3-b] pyridin-3-carbonyl) -2-fluoro-phenyl] -amide, N- [3- (5-cyano-1H-pyrrole [2 , 3-b] pyridin-3-carbonyl) -2,4-difluoro-phenyl] -2,5-difluoro-benzenesulfonamide, N- [3- (5-cyano-1H-pyrrole [2,3-b] pyridin -3-carbonyl) -2,4-difluoro-phenyl] -3-fluoro-benzenesulfonamide, [3- (5-cyano-1H-pyrrole [2,3-b] pyridin-3-carbonyl) -2,4- pyrrolidin-1-sulfonic acid difluoro-phenyl] -amide, [3- (5-cyano-1H-pyrrole [2,3-b] pyridin-3-carbonyl) -2,4-difluoro-phenyl] -amide N, N-dimethylaminosulfonic acid, and its salts, formulations, conjugates, derivatives, forms and uses. In certain aspects and embodiments, the described compounds, or their salts, formulations, conjugates, derivatives and forms are active for at least one Raf protein kinase. Methods of using them to treat diseases and conditions, including the diseases and conditions associated with the activity of Raf protein kinases, including melanoma, glioma, colorectal cancer, thyroid cancer, lung cancer, ovarian cancer, cancer are also described. of prostate and biliary tract cancer. |
| priorityDate | 2009-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.