http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-075398-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a9e6421e9257148abad101e1ce6c162 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-454 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D407-04 |
filingDate | 2010-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44c4117ca89c19bb5389938f52b58ce7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1b7f737da5ad5f55849fcb9062601e2 |
publicationDate | 2011-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | AR-075398-A1 |
titleOfInvention | DERIVATIVES OF 3-BENZOFURANIL-INDOL-2-ONA-3-ACETAMIDOPIPERAZINAS REPLACED, ITS PREPARATION AND ITS APPLICATION IN THERAPEUTICS |
abstract | Preparation procedure and therapeutic application of said compounds. Claim 1: Compound that responds to formula (1): wherein: R 1 represents a hydrogen atom or a C 1-6 alkyl group, -C (= O) -C 1-6 alkyl or -C (= O) - aryl; R2, R3 and R4, identical or different, located in any of the available positions of the phenyl nucleus, independently represent a hydrogen atom, a halogen atom, CN, OH, a C1-6 alkyl group optionally substituted with an atom halogen or an OH; C1-3 perhaloalkyl, C1-6 alkoxy, C1-3 perhaloalkoxy, aminocarbonyl, C1-6 alkyl aminocarbonyl, di- C1-6 alkyl aminocarbonyl, aryl, aryloxy or heteroaryl; the aryl, aryloxy or heteroaryl group may optionally be substituted with a halogen atom, CN, OH or a C1-6 alkyl, C1-3 perhaloalkyl or C1-6 alkoxy group; it being understood that at least one of R2, R3 and R4 is different from H and that the aryl, aryloxy or heteroaryl group may eventually be substituted with a halogen atom, CN, OH or a C1-6 alkyl group, C1-3 perhaloalkyl or C1-6 alkoxy; R5 and R6, identical or different, represent a hydrogen atom, a C1-6 alkyl group or R5 and R6 together form a cycle of C3-6 carbon atoms; R7 represents a C1-6 alkyl group or a C2-6 alkenyl group; R8 and R9, located on any one of the available positions of the piperazine ring, represent a hydrogen atom, a C1-6 alkyl group or a C2-6 alkenyl group, it being understood that at least one of R8 and R9 is different from H; or two of R7, R8 and R9 together form a cycle of C3-6 carbon atoms; it being understood that R8 and R9 can be in geminal position on the same carbon atom; n represents 1 or 2; in the form of base or salt of addition of an acid. |
priorityDate | 2009-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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