http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-075394-A1
Outgoing Links
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filingDate | 2010-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2011-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | AR-075394-A1 |
titleOfInvention | DERIVATIVES OF THE PHENOXYACETIC ACID, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM, METHOD OF PREPARATION AND USE OF THE SAME IN THE TREATMENT OF INFLAMMATORY, ALLERGIC AND NEURODEGENERATIVE DISEASES. |
abstract | Claim 1: A compound of the formula (1) as well as its ester derivatives, its geometric isomers, its optically active enantiomers, diastereoisomers and its forms of racemates and tautomers or one of its pharmaceutically acceptable derivatives, wherein R1 is H, Hal , A, CN, NO2, OA, CF3, OCF3, Ar or Het, Q is Ar, Het, n is 0, 1, 2, 3 or 4, m is 0, 1 or 2 where n + m is not 0 , z is phenyl, naphthyl or pyridinyl, A is branched or linear alkyl having 1 to 12 C atoms, where one or more, preferably 1 to 7 H atoms can be replaced by Hal, OR3, CN or N ( R3) 2 and wherein one or more, preferably 1 to 7 non-adjacent CH2 groups may be replaced by O, NR3 or S and / or by groups CH = CH- or -C? C- or denotes cycloalkyl or cycloalkylalkylene having 3 to 7 C atoms of the ring, Hal is F, Cl, Br or I, Ar denotes an unsaturated or aromatic monocyclic or bicyclic carbocyclic ring having 6 to 14 carbon atoms that may not be substituted or which may be monosubstituted, disubstituted or trisubstituted or tetrasubstituted with Hal, A, -CH2OA, -CH2SO2A, -CH2OR3, -OR3, CF3, -OCF3, -N (R3) 2, NO2, -CN, -NR3COA, -NR3COAr ', -NR3SO2A, -COR3, WITH (R3) 2, COHet, -SO2N (R3) 2, -SOA, -SO2A, Het or with SO2t, SOT, Ar', T denotes - (CH2) p-Ar 'or - (CH2) p-Het ', p is 0, 1, 2, 3 or 4, Ar' denotes an unsaturated monocyclic or bicyclic carbocyclic ring p having 6 to 14 carbon atoms that may not be substituted or that may be monosubstituted, disubstituted or trisubstituted with Hal, A, -CH2OA, -CH2OR3, -OR3, -CF3, -OCF3, -Het 'denotes a monocyclic or bicyclic, saturated, unsaturated or aromatic heterocyclic ring having 1 to 4 N atoms, O and / or S, which may not be substituted or which may be monosubstituted, substituted or trisubstituted with Hal, A, CH2OA, OR3, CF3, OCF3, Het denotes a monocyclic or bicyclic or tricyclic heterocyclic ring, unsaturated or aromatic, having 1 to 4 atoms of N, O, S, and / or 1 group S O2, and / or CO and / or NO groups, which may not be substituted or that may be monosubstituted, substituted or trisubstituted or tetrasubstituted with Hal, A, CH2OA, OR3, CF3, OCF3, N (R3) 2, NO2, CN , NR3COA, NR3SO2A, COR3, SO2N (R3) 2, SOA, SO2A, SO2t, R3 is H or A, Rx, Ry denote, independently, H, a linear or branched alkyl having 1 to 8 carbon atoms optionally substituted with OH, Hal, CN or Rx and Ry together form a carbocyclic ring having 3 to 7 carbon atoms, optionally substituted with OH, Hal, CN. |
priorityDate | 2009-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.