http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-074632-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 |
| filingDate | 2009-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-074632-A1 |
| titleOfInvention | AMIDOFENOXIINDAZOL COMPOUND, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT AND ITS USE TO PREPARE A USEFUL MEDICINAL PRODUCT IN CANCER TREATMENT |
| abstract | An amidophenoxyindazole compound of the formula (1), wherein: R 1 is H or methyl; R2 is amino, dimethylamino, fluoro, cyclopropyl, pyridyl optionally substituted with an amino substituent or 1-2-methyl substituents, pyrazolyl optionally substituted with two methyl substituents, 2-methoxy-pyrimidin-5-yl, 4-methylosulfonylphenyl, tetrahydro-2H -piran-4-ylamino, (tetrahydro-2H-pyran-4-yl) amino carbonyl, or a morpholin-4-yl substituent of formula (2), wherein, Ra, Rb and Rc are independently selected from H or methyl; R3 is H or F; R4 is H, methyl, piperidin-1-ylmethyl, morpholin-4-ylmethyl, or pyrazol-1-ylmethyl; R5 is H or F; and X is CH = N, CH = CH, CH = C (CH3), C (CH3) = CH, C (CH3) = N, N (CH3), or C (morpholin-4-ylmethyl) = CH; or a pharmaceutically acceptable salt thereof. Pharmaceutical composition that comprises it and its use to prepare a medicine useful in the treatment of cancer. |
| priorityDate | 2008-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.