abstract |
The pharmaceutical solid oral preparation which is prepared by the process comprising the wet granulation of conventional crystals of anhydrous Aripiprazole, the drying of the granules obtained at 70-100 ° C and the classification thereof according to size, then new drying of the granules classified at 70-100 ° C where said pharmaceutical solid oral preparation has at least one dissolution rate selected from the group consisting of 60% or more with a pH 4.5 after 30 minutes, 70% or more with a pH 4.5 after 60 minutes, and 55% or more with a pH 5.0 after 60 minutes. The pharmaceutical solid oral preparation that is prepared by the process comprising the wet granulation of conventional Aripiprazole hydrate crystals, the drying of the granules obtained at 70-100 ° C and the classification thereof according to size, then new drying of the granules classified at 70-100 ° C where said pharmaceutical solid oral preparation has at least a dissolution rate selected from the group consisting of 60% or more with a pH 4.5 after 30 minutes, 70% or more with a pH 4.5 after 60 minutes, and 55% or more with a pH 5.0 after 60 minutes. |