http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-073037-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c89ce4d9ac03f9acd8ddede1162f94d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N43-653 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J71-0005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4196 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J63-008 |
| filingDate | 2009-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b931350ee66b5593d707c7bbb35c1f8b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bae8d0b87637e08140ec3df2f30efe8b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfb4224dedc1b9a54a07b98ee473b6b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fef994ff96a2c5e640a57f200cf47db1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df52e8509d5b3b56d5e226e490729294 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_757f459fbb4de5a610565db76f4509e7 |
| publicationDate | 2010-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-073037-A1 |
| titleOfInvention | ENFUMAFUNGINA DERIVATIVES, USEFUL IN THE INHIBITION (1,3) -BETA-D-GLUCANO SINTASA |
| abstract | Derumafungin derivatives are described, together with their pharmaceutically acceptable salts, hydrates and prodrugs. Compositions comprising said compounds, methods for preparing said compounds and methods for using said compounds as antifungal agents and / or (1,3) -beta-D-glucan synthase inhibitors are also described. The described compounds, their pharmaceutically acceptable salts, hydrates and prodrugs, as well as the compositions comprising said salts, hydrates and prodrugs, are useful for treating and / or preventing fungal infections and associated diseases and conditions. Claim 1: A compound of the formula (1); or a pharmaceutically acceptable salt thereof, characterized in that: X is O or H, H; Rc is C (O) NRfRg or a 6-membered ring heteroaryl group containing 1 or 2 nitrogen atoms, wherein the heteroaryl group is optionally mono-substituted on a ring carbon with fluoro or chloro or on a nitrogen of the ring with oxygen; Rf, Rg, R6 and R7 are each independently hydrogen or C1-3 alkyl; R8 is C1-4 alkyl, C3-4 cycloalkyl, or C4-5 cycloalkyl; R9 is methyl or ethyl; and R8 and R9, optionally, are taken together to form a 6-member saturated ring containing 1 oxygen atom. |
| priorityDate | 2008-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.